Obtain normal values of ventricle volumes and CSF circulation in healthy volunteers with MRI scanning.
ID
Source
Brief title
Condition
- Increased intracranial pressure and hydrocephalus
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Ventricle volumes and CSF circulation or flow
Secondary outcome
n.a.
Background summary
Several studies on hydrocephaly are ongoing. For these studies, normal values
of healthy volunteers are needed. Up to now, normal values are not or are
insufficiently available. This currently proposed study will obtain normal
values of ventricle volumes and CSF circulation.
Study objective
Obtain normal values of ventricle volumes and CSF circulation in healthy
volunteers with MRI scanning.
Study design
this is an observational study without intervention.
Study burden and risks
Participation in this study costs little time: time for inclusion, once
travelling and scanning. Patients who are not allowed in the MRI scanner are
excluded (e.g. with pace maker of claustrophobia). There are no known side
effects of MRI scanning. It is in theory possible that a lesion in the brain is
discovered during this study. This could have a positive effect: the patient
who did not have symptoms yet can be treated at a very earlystage of the
disease. On the other hand, a negative effect is possible: a untreatable lesion
is discovered and the healthy volunteer will become a patient. Or else, a
lesion that does not need treatment is found.
However, the scanning sequences are designed for volume measurement and flow
measurement, and are not dedicated sequences for discovery of lesions.
geert grooteplein zuid 10
6525 GA
Nederland
geert grooteplein zuid 10
6525 GA
Nederland
Listed location countries
Age
Inclusion criteria
healthy
age 18-50 year
no contra-indications for MRI scan
Exclusion criteria
hydrocephaly / CSF circulation disorder
exclusion criteria for MRI for example pacemaker, claustrofobia
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL25966.091.09 |