The primary research question is:1. Is there a difference in the usage of memory strategies between both groups?The secundary research questions are:2. Is there a difference between both groups in the types of memory strategies they use or don*t use…
ID
Source
Brief title
Condition
- Mood disorders and disturbances NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary research variables are the differences in testresults on the
memorytasks between the both groups. It is expected that the elderly with an
affective disorder wil get the lower scores on these tasks compared with the
healthy group.
Secondary outcome
The secundary research variables are the differences in types of memory
strategies and the differences in the amount of complaints between both groups.
It is expected that the elderly with an affective disorder wil use less
efficiënt memory strategies, measured by the questionnaire on memory strategy
use in daily life and reported in the interview. Also it is expected that they
will report more complaints on the questionnaire on cognitive complaints.
Furthermore, it is expected that elderly with a lot of cognitive complaints are
using less effective memory strategies. This will be found in lower scores on
the memorytasks for the elderly who have high scores on the complaint
questionnaire. And it is expected that elderly who score high on the complaints
will report that they use less memory strategies in daily life (on the
questionnaire).
Background summary
This study is a first study that is part of a larger project on developing a
psychosocial memory strategy training for elderly with a chronic depression.
The goal of the present study is to find out if there is a difference between
the usage of memory strategies between elderly who recieve treatment for a
longer existing affective disorder and healthy elderly. It is expected that the
depressive elderly will be using less effective memory strategies than the
healthy controlgroup will do. For the development of the training it is assumed
that the depressive elderly can be trained in using memory strategies. The
present study also makes clear which cognitive complaints these patients are
having, what knowledge they have about memory and memory strategy usage and
what they would like to learn if they get a training. This way the training
will be totally adjusted to the wishes and needs of the patients.
Study objective
The primary research question is:
1. Is there a difference in the usage of memory strategies between both groups?
The secundary research questions are:
2. Is there a difference between both groups in the types of memory strategies
they use or don*t use? In other words: do healthy elderly use different (more
effective) memory strategies than depressive elderly use?
3. Is there a difference between both groups in subjective cognitive complaints?
4. Is there a relation between the number of subjective cognitive complaints
and the number of memory strategy use?
Study design
The present study is an observational research without invasive measurements
(according to the ABR-form). The participants will get, after a few short tests
for screening the in/exclusion criteria, a couple of memorytasks and
questionnaires. After that, they will be interviewed. By using T-tests
primarily, but also some non-parametric tests for the secundary research
questions, the four research questions and -hypotheses will be statistically
processed.
Study burden and risks
The psychodiagnostic procedure (containing a couple of short tests for the
in/exclusioncriteria, an interview, 2 questionnaires and neuropsychological
tasks) will take at a maximum 2 hours and will be done in one go. The research
is without risk for the participants and is not invasive. As seen in the short
pilotstudy we have already done, it was just a small effort for these
participants to participate.
Albrandswaardsedijk 74, Postbus 800
3170 DZ Poortugaal
Nederland
Albrandswaardsedijk 74, Postbus 800
3170 DZ Poortugaal
Nederland
Listed location countries
Age
Inclusion criteria
chapter 4.2 protocol
Inclusion criteria patients:
• age >=60
• patients with a chronic depression, depression partly in remission or dysthyme, according to DSM-IV criteria, receiving treatment
• affective disorder must exist over at least 6 months (psychofarmacological treatment is allowed, but the name and dosis of the drug must be known)
• Scores on the Geriatric Depression Scale (GDS) between 11 en 19 (mild depressive symptoms)
• Scores on the Mini-Mental State Examination (MMSE) equal or higher than 25
• Scores on the Visuele Associatie Test (VAT) higher than percentile 10;chapter 4.4
inclusion criteria healthy elderly:
• age >= 60
• no psychiatric problems in history nor current
• GDS<11
• MMSE >= 25
• VAT> percentile 10
Exclusion criteria
chapter 4.3 exclusion criteria patients:
• Patients who might have dementia or delirium and patients with MMSE-scores lower than 25 at the start of the research
• GDS<11 (no depressive symptoms) of GDS >19 (severe depressive symptoms)
• Severe behavioral problems, psychiatric or cognitive problems (for example CVA, but also other DSM-IV diagnoses or personality disorders), which cause that the patient cannot be instructed or cause that the patient is not suitable for a testsession
• Extreme and invalidating fysical or conditional problems
• Patients who cannot travel to the testlocation in Poortugaal
• VAT<= percentile 10
• Estimated verbal IQ< 90 measured by the Nederlandse Leestest voor Volwassenen (NLV);chapter 4.5 exclusion criteria healthy elderly:
• Elderly who might have dementia or delirium and elderly with MMSE-scores lower than 25 at the start of the research
• GDS >=11
• Having psychiatric problems currently or in history
• Severe behavioral problems, psychiatric or cognitive problems (for example CVA, but also other DSM-IV diagnoses or personality disorders), which cause that the elderly cannot be instructed or cause that the elderly is not suitable for a testsession
• Extreme and invalidating fysical or conditional problems
• cannot travel to the testlocation (in Poortugaal or elsewhere in the Netherlands)
• VAT<= percentile 10
• Estimated verbal IQ< 90 measured by the NLV
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL20300.097.08 |