To investigate the effects on satiety parameters of teff bread relative to wheat bread in healthy individuals. The secondary objectives are to study the effects of teff energy intake and on fermentation in the large bowel.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
indicatoren voor energie inname
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is subjective satiety after a test breakfast.
Secondary outcome
Secondary parameters are total energy intake after 4.5 hours and carbohydrate
fermentation.
Background summary
No scientific evidence is available regarding the effects on satiety of food
products containing Eragrostis Tef (teff).
Study objective
To investigate the effects on satiety parameters of teff bread relative to
wheat bread in healthy individuals. The secondary objectives are to study the
effects of teff energy intake and on fermentation in the large bowel.
Study design
Three test foods will be consumed in a randomized crossover trial. The foods
will be offered to each subject during three separate test days. 4.5-hour
postprandial satiety and breath hydrogen will be measured, followed by an ad
libitum meal.
Intervention
Per test day, subjects will receive a 100 g portion of test foods, which they
ingest within 10 -15 minutes. The test foods are breads baked with different
types of flour/meal developed by *Koopmans meel b.v.* (Leeuwarden). All
ingredients of the products are suitable for human consumption and are
microbiologically safe. Of the wheat flour 35% will be exchanged for wheat
meal, and teff meal. Every 30 minutes for the following 4.5 hours satiety
parameters will be measured at a visual analogue scale and hydrogen will be
measured by means of a breath sample. After 4.5 hours an ad libitum meal will
be consumed.
Study burden and risks
The intervention is non-therapeutic to the participant. The risk associated
with participation is negligible and the burden can be considered as low. In
the trial subjects have to come to the research centre once for a screening
visit during which several questionnaires are filled out and anthropometrics
are measured. In the trial, subjects have to come to the research centre 3
times for approximately 5 hours, during which the effect on satiety will be
measured for 4.5 hours, breath samples will be taken and an ad libitum test
meal will be eaten. All test foods are based on commercially available products
and are safe to use for human consumption.
Agora 1
8934 AK Leeuwarden
Nederland
Agora 1
8934 AK Leeuwarden
Nederland
Listed location countries
Age
Inclusion criteria
Age: 18-50 year
BMI: 18-25 kg/m2
Healthy: as judged by the participant
Exclusion criteria
Diabetes, or any endocrine disorder
Hypersensitivity for gluten or bread products
Weight loss or weight gain of more than 5 kg during the last 2 months
Using an energy restricted diet during the last 2 months
Lack of appetite for any (unknown) reason
Restrained eater
Frequent and high intensity physical active
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL26020.081.08 |