The primary objective of this study is to determine the glycaemic index of palm sugar in healthy adults
ID
Source
Brief title
Condition
- Glucose metabolism disorders (incl diabetes mellitus)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Blood glucose concentrations taken at baseline and at increasing intervals up
to and including 120 minutes after ingestion of the sugar to calculate the
glycaemic index of palm sugar.
Secondary outcome
Not applicable
Background summary
There is no scientific evidence available regarding the glycaemic index of palm
sugars. It has also been claimed by many that the glycaemic index of palm sugar
is extremely low (less then 30). Therefore a study determining the glycaemic
index of palm sugar is warranted to provide evidence for or against these
claims.
Hypothesis: The GI of palm sugar is approximately 68; equal to that of sucrose
which is 68.
Study objective
The primary objective of this study is to determine the glycaemic index of palm
sugar in healthy adults
Study design
Double blind randomized cross over design
Intervention
On each of the five measurement days study participants will receive either 50
g of palm sugar, sucrose or glucose which they need to ingest within 5 to 10
minutes. At time points 0, 15, 30, 45, 60, 90, 120 minutes1 blood sample will
be taken. On the first and last day of the study the participants will receive
glucose on the other 3 days they will receive either palm, sucrose or glucose
in a randomised order.
The test sugar, palm sugar, is produced in Sumatra Indonesia and has been made
for human consumption.
Study burden and risks
This intervention is non-therapeutic to the test subject. During the
intervention a standard lancing will be used by a trained investigator to take
seven blood samples per session. As a result of this, or the fasting,
participants will have small wounds on their fingers and may experience
feelings of light-headedness, dizziness or fainting. The risks are however
minimal. The sugar used in this study is produced for human consumption, and
therefore the risk and burden to the participants for participating in this
study can be considered minimal.
Bomenweg 4
6703 HD Wageningen
NL
Bomenweg 4
6703 HD Wageningen
NL
Listed location countries
Age
Inclusion criteria
Healthy as judged by the participant;
Aged 18 to 35
Exclusion criteria
Pregnant or lactating females;
Presence of a chronic disease such as diabetes, cardiovascular illness, dysmetabolic syndrome;
18.5 > BMI > 25;
Allergy or intolerance to palms or coconuts;
Weight loss or gain of more then 5 kg in the last two months
Fasting blood glucose levels <100 mg/dl or 5.6 mmol/l;
Smokers;
Use of medications other then birth control;
Previous problems with blood sampling
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL33657.081.10 |