Functional MRI guided transcranial magnetic stimulation of the oculomotor system

People are able to quickly and often completely automatically adapt their motor
responses to a dynamic environment. The human oculomotor system serves as a
model for this remarkable adaptation abilities of the human motor system. The
exact contribution of the various brain areas to this process is unclear,
however.

Investigating the influence of Transcranial Magnetic Stimulation
(TMS)-disruptions on the neural processes in the areas involved in the
adaptation abilities of the human oculomotor system.

Five experimental studies will be conducted in which eye movements have to be
made under various dynamic conditions. During three experiments TMS will be
applied to measure the influence of the disruptions. In two experiments, a
number of brain areas and connections will be visualized on individual basis
using functional magnetic resonance imaging (fMRI) and DTI (diffusion tensor
imaging).

Because of the apllied TMS parameters, there will be no significant health
risk. The stimulation itself can sometimes be somewhat uncomfortable and lead
to a light headache during stimulation. The headache can be effectively treated
with light analgetics like aspirine.
The applied fMRI techniques do not constitute a safety risk for the
participants when one restricts oneself to the general used rules for
conducting a fMRI experiment.