1. To determine the level of cognitive, emotional and cardiorespiratory impairment, daily functioning, participation in society, quality of life and partner strain up to one year after the survival of a cardiac arrest.2. To determine prognostic…
ID
Source
Brief title
Condition
- Cardiac arrhythmias
- Encephalopathies
- Cognitive and attention disorders and disturbances
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Participation in society and quality of life.
Secondary outcome
Cognitive, emotional and cardiorespiratory impairment, daily functioning and
caregiver strain.
Background summary
Although more and more is known about the pathophysiology and acute care of
cardiac arrests, information about long-term consequences and prognostic
factors for future functioning are lacking. A substantial number of cardiac
arrest survivors suffer from hypoxic brain injury what can result in cognitive
problems. However, these cognitive impairments are frequently not recognised.
This can lead to limitations in daily functioning and participation, what is
expected to lead to a decreased experienced quality of life in the patient, and
a high strain for the caregiver. As the number of cardiac arrest survivors is
expected to increase, due to the faster access to external defibrillators, more
knowledge on the quality of survival is essential. Also the effect of a
follow-up programme by a specialised nurse, what is currently not existing,
should be examined.
Study objective
1. To determine the level of cognitive, emotional and cardiorespiratory
impairment, daily functioning, participation in society, quality of life and
partner strain up to one year after the survival of a cardiac arrest.
2. To determine prognostic factors for cognitive impairment, daily functioning,
participation in society, and quality of life one year after a cardiac arrest.
3. To perform an effect and economic evaluation of a routine early intervention
service.
Study design
Prospective cohort study with a nested randomised controlled clinical trial.
Intervention
The intervention group receives a routine early intervention service consisting
of several contacts with a specialised nurse. The intervention is directed at
early detection of (cognitive) problems, information supply and provision of
support to the patients and their caregiver. If indicated, the patient can be
referred to specialised care. The control group receives care as usual.
Study burden and risks
This study will have a low burden and has minimal risks associated with
participation. The burden for all participants consists of three measurements
during one year. Participants who also take part in the randomised controlled
trial also have to fill out a cost diary or questionnaire. Half of the
participants in the randomised controlled trial will be allocated to the early
intervention service, and will receive extra attention and care, what is
expected to be perceived positively.
Zandbergsberg 111
6432 CC Hoensbroek
NL
Zandbergsberg 111
6432 CC Hoensbroek
NL
Listed location countries
Age
Inclusion criteria
Survivor of a cardiac arrest
Survival after cardiac arrest > 2 weeks
Admitted in or to one of the participating hospitals
Living within 50 km of one of the participating hospitals
18 years or older
Sufficient knowledge of Dutch language
Exclusion criteria
General: Severe non-cardiac co-morbidity with a life expectancy lower than 3 months.
For participation in randomised controlled trial: Participant was living in an institutional care facility prior to the cardiac arrest.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL15753.068.06 |