to study testicular volumes after inguinal herniotomy at childhood.
ID
Source
Brief title
Condition
- Testicular and epididymal disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
testicular volume, measured by ultrasound
Secondary outcome
testicular position and volume measured by Prader orchidometer
Background summary
Testicular atrophy is a complication after inguinal herniotomy in children.
Percentage described in the literature varies from 1 to 38% [1-4].
It is imaginable inguinal operation at childhood has his long-term effects. The
funniculus, with spermatic fascia, cremaster muscle, ductus deferens, spermatic
artery and vein, can be damaged. This can cause a reduce in growth -and
function [5]- of the testicle.
The Leung et al. [6] studied the precize volumina of the testicles after
herniotomy at childhood [6]. They documented in 0.58 and 10% of the boys a
respectively more than 50 en 25% decrease in testicular volume on the operated
side when compared with the non-operated side.
An important limitation of this study is -as described in their discussion-
'the testicular volumes of the operated and normal sides of the same patient
were compared since we believe it is very difficult, if not impossible, to
obtain a 'normal range' of testicular volume in a specific age group.
Because our research group recently created this 'normal ranges', we hope to
improve the study of testicular volume after inguinal herniotomy at childhood.
1. Friedman, D., Schwartzbard, A., Velcek, F. T. et al.: The government and the
inguinal hernia. J Pediatr Surg, 14: 356, 1979
2. McGregor, D. B., Halverson, K., and McVay, C. B.: The unilateral pediatric
inguinal hernia: Should the contralateral side by explored? J Pediatr Surg, 15:
313, 1980
3. Puri, P., Guiney, E. J., and O'Donnell, B.: Inguinal hernia in infants: the
fate of the testis following incarceration. J Pediatr Surg, 19: 44, 1984
4. Surana, R. and Puri, P.: Is contralateral exploration necessary in infants
with unilateral inguinal hernia? J Pediatr Surg, 28: 1026, 1993
5. Takihara, H., Cosentino, M. J., Sakatoku, J. et al.: Significance of
testicular size measurement in andrology: II. Correlation of testicular size
with testicular function. J Urol, 137: 416, 1987
6. Leung, W. Y., Poon, M., Fan, T. W. et al.: Testicular volume of boys after
inguinal herniotomy: combined clinical and radiological follow-up. Pediatr Surg
Int, 15: 40, 1999
Study objective
to study testicular volumes after inguinal herniotomy at childhood.
Study design
study population
inclusion:
- boys who underwent inguinal herniotomy between 1999-2008 - acute or elective-
before the age of 16 years in the Medical Centre Alkmaar.
- age at follow-up 9-13 years.
exclusion:
- abnormalities at scrotum / testis (eg torsio testis)
- chromosomal abnormalities
Ca. 200 boys will reach the inclusion criteria. With a response of 50% we will
include ca. 100 boys.
clinical examination
* position of the testes
* testicular volume
- prader orchidometer
- ultrasound
data will be analysed by SPSS
Study burden and risks
One visit to the outpatient clinic for a pain-free clinical examination without
any risk.
Wilhelminastraat 12
1815 JD Alkmaar
NL
Wilhelminastraat 12
1815 JD Alkmaar
NL
Listed location countries
Age
Inclusion criteria
- male
- inguinal hernitomy between 1999 - 2008 before the age of 16 years in the medical Centre Alkmaar
- age of 9-13 years at the time of follow-up.
Exclusion criteria
- abnormalities of scrotum of testis (eg. torsio testis)
- chromosomal abnormalities
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL29613.094.09 |