The objective of this study is to determine the effect of retinal illuminance on TCS outcome.
ID
Source
Brief title
Condition
- Vision disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study parameter is the measured temporal contrast sensitivity value
Secondary outcome
N/A
Background summary
In clinical practice it is relatively easy to assess conditions of the eye that
are related to the eye-optics. However, conditions that predominantly affect
retinal or neuronal functioning are far more difficult to assess due to absence
of a good screening device.
Temporal contrast sensitivity (TCS) can be used to assess pure retinal and
neuronal functioning of the eye and is independent of optical deficits of the
eye. TCS may therefore be used as a screening and or follow-up method for
retinal diseases, such as glaucoma and RP. However, the TCS is dependent on the
retinal illumination which may be affected by the pupil diameter and aging of
the eye lens. For this reason the aim of this study is to investigate (and
quantify) the effect of retinal illuminance, due to varying pupil diameter and
light level, on the TCS outcome.
Study objective
The objective of this study is to determine the effect of retinal illuminance
on TCS outcome.
Study design
Observational study. In 10 healthy volunteers the influence of light level on
TCS outcome is observed.
Study burden and risks
For this study the pupil needs to be dilated, as is usual routine in
ophthalmology. Risks are negligible.
NIN meibergdreef 47
1105 BA, Amsterdam
NL
NIN meibergdreef 47
1105 BA, Amsterdam
NL
Listed location countries
Age
Inclusion criteria
normal healthy eyes without any history of ocular disease
Exclusion criteria
any presence or history of ocular pathologies or other disorders, especially retinal and/or neuronal disorders
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL38513.018.11 |