To explore the association between MBL level at baseline and the incidence of febrile neutropenia.
ID
Source
Brief title
Condition
- Bacterial infectious disorders
- Miscellaneous and site unspecified neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To explore the association between MBL level at baseline and the incidence of
febrile neutropenia.
Secondary outcome
To explore the prognostic value of MBL-genotype on the incidence and severity
of febrile neutropenia
To explore whether the MBL level is different prior to chemotherapy cycle 2
compared to baseline.
To explore the association between MBL level at baseline and the severity of
febrile neutropenia during the first course
To explore the association between MBL level at baseline and the incidence and
severity of febrile neutropenia during the first 2 courses
To explore the association between MBL level at baseline and the incidence and
severity of febrile neutropenia during the treatment period
To explore the association between MBL level before the second course and the
incidence and severity of febrile neutropenia during the 2nd course
To describe the change in MBL levels during a FN episode.
To explore the potential change in MBL levels during a FN episode to severity
of FN.
Background summary
Febrile neutropenia is a threatening complication of chemotherapy. Assessment
of the risk of suffering from febrile neutropenia, before the initiaition of
chemotherapy is important
Study objective
To explore the association between MBL level at baseline and the incidence of
febrile neutropenia.
Study design
cohort study
Study burden and risks
collection of 20 ml extra blood
Kleiweg 500
3045PM
NL
Kleiweg 500
3045PM
NL
Listed location countries
Age
Inclusion criteria
Treatment with chemotherapy for solid malignancy
Exclusion criteria
Treatment with growth factor supoort and/or antibiotics
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL37499.099.11 |