Our aim with this research program is to understand (1) cognitive processes during sleep onset, (2) (advanced, functional) EEG-correlates of sleep onset, (3) their interaction and (4) how these relate to the resting state.
ID
Source
Brief title
Condition
- Sleep disorders and disturbances
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Characterize and relate EEG, RSQ50 scores and their interaction during sleep
onset and resting wakefulness.
Secondary outcome
Extract relevant EEG and cognitive parameters that can be used to successfully
predict sleep onset and/or provide feedback on.
Background summary
Insomnia is a prevalent disorder that is frequently pharmacologically treated.
Hallmark of the disorder is the inability to fall and/or stay asleep, which is
often accompanied by cognitive hyperarousal. Knowing more about the cognitive
and EEG predictors of the sleep onset period may help characterize the disorder
further and also derive more effective strategies to guide subjects towards
more efficient sleep. Furthermore, mapping EEG and cognitive correlates will
potentially guide the development of alternative treatment methods such as
EEG-based biofeedback.
Study objective
Our aim with this research program is to understand (1) cognitive processes
during sleep onset, (2) (advanced, functional) EEG-correlates of sleep onset,
(3) their interaction and (4) how these relate to the resting state.
Study design
Nine sessions of sleep onset matched to nine sessions of wakefulness, simialr
to the protocol employed by Raymann et al. (2005). Each session is recorded
using high-density EEG and followed by the RSQ50 (Linkenkaer-Hansen, 2011).
Study burden and risks
Subjects will visit the lab on two consecutive days. Each day nine measurements
will be made, which will alltogether last a maximum of 8 hours. During each
measurement the subject will be lying in a comfortable bed for a maximum of 30
minutes. Afterwards a computerized version of the questionnaire will be
administered. Mounting of the EEG-cap will take 45 minutes in total, the cap
itself consist of 256 sensors, distributing the weight of the head comfortably.
Preparation of the subject only entails washing the hair * no other possibly
discomforting actions (e.g. skin scrubbing etc.) are necessary. We judge
subject discomfort to be minimal.
De Boelelaan 1085
1081 HV Amsterdam
NL
De Boelelaan 1085
1081 HV Amsterdam
NL
Listed location countries
Age
Inclusion criteria
* Healthy human individuals
* Dutch or English speaking
* Non-smoking
* Age 18-55
* No history of prior neurological problems (e.g. epilepsy, head trauma etc.)
* Having signed informed consent
Exclusion criteria
History of drug abuse
Psychiatric disorders
Sleep disorders
Medication
History of epilepsy
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL36820.029.11 |