In this randomised controlled trial we compare three commonly used preventive methods to reduce the pain on injection op (PIP) with a control group. Our primary goal is to try and establish the most effective and easy to use method for preventing…
ID
Source
Brief title
Condition
- Administration site reactions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Our primary goal is to try and establish the most effective and easy to use
method for preventing PIP, without slowing induction of anaesthesia.
Secondary outcome
Secondary goal is to try and find a correlation between pain on IV-cannulation
and the experience of PIP.
Background summary
Pain upon injection of the most commonly used narcotic propofol is a frequently
occurring problem on induction of anaesthesia. Several preventive methods have
been described to reduce the incidence and severity of this pain, but until now
no method has been described as best clinical practise yet.
Study objective
In this randomised controlled trial we compare three commonly used preventive
methods to reduce the pain on injection op (PIP) with a control group. Our
primary goal is to try and establish the most effective and easy to use method
for preventing PIP, without slowing induction of anaesthesia. Secondary goal is
to try and find a correlation between pain on IV-cannulation and the experience
of PIP.
Study design
randomised controlled trial
Study burden and risks
-
Michelangelolaan 2
5623 EJ Eindhoven
NL
Michelangelolaan 2
5623 EJ Eindhoven
NL
Listed location countries
Age
Inclusion criteria
ASA 1 and 2 patients, aged 18-80 years, who will undergo an elective surgical procedure under general anaesthesia
Exclusion criteria
use of NSAIDs or opiates on a regular basis or if communication of psychological disorders are present. Further exclusion criteria are history of polyneuropathy, pre-existing underlying pathology associated with pain, known hypersensitivity to lidocaine, propofol, lipid emulsions, egg or egg products, emergency surgery, pregnancy and patients using antidepressant medications
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL36325.060.11 |