The aim of this study was to investigate the effect of an antiseptic mouthwash and tongue hygiene on the concentration of volatile sulphur compounds and morning bad breath in periodontal healthy subjects.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Slechte ochtend adem
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome is moring Bad Breath and will be measured by three
different methods
Organoleptic score:
The judge is using an arbitrary 0-5 scale (Rosenberg et al. 1991a, Rosenberg et
al. 1991b further modiefied by Greenman et al. 2004). The 0 represented absence
of odour, 1 was given for barely noticeable odour, 2 for slight odour, 3 for
moderate odour, 4 for strong odour and 5 for extremely strong odour.
Halimeter:
We are using a portable industrial sulphide monitor (Halimeters, Interscan
Corp., Chatsworth, CA, USA). The unit is zeroed to ambient air before each
measurement, using the technique established by Rosenberg et al. (1991a, b).
OralChroma assessments:
A portable gas chromatography (OralChroma®) using a flame photometric detector
is the preferable method if precise measurements of specific gases are
required. This technology is specifically designed to digitally measure
molecular levels of the three major VSC (H2S, CH3SH, and dimethyl sulfide
CH3SCH3).
Secondary outcome
Tongue coating index:
The procedure to assess coating is a modification of the method as described by
Miyazaki et al. (1995) and described in detail by Mantilla Gomez et al. (2001).
Enquete: subjects give their opinions about their experience of this clinical
trial
Background summary
Halitosis is a general term used to describe an unpleasant or offensive odor
emanating from the oral cavity. Several (non-oral) pathological conditions have
been related to oral malodor, including infection of the upper and lower
respiratory tracts, the gastrointestinal tract, and some metabolic diseases
involving the kidneys or the liver (Manolis 1983). However, clinical surveys
have shown that around 90% of all bad breath odors originate in the mouth
(Delanghe et al. 1997). Oral halitosis is the specific term used to define
halitosis with an origin within the oral cavity
Study objective
The aim of this study was to investigate the effect of an antiseptic mouthwash
and tongue hygiene on the concentration of volatile sulphur compounds and
morning bad breath in periodontal healthy subjects.
Study design
This is a parallel blind, randomized, clinical trial of 3 months
The trial will take 3 weeks for each person.
Intervention
The control group: use fluoride toothpaste Everclean ® HEMA, which is available
on the market.
Intervention (test) group: use Meridol ® Halitosis: toothbrush, toothpaste,
mouthwash and tongue cleaner.
Study burden and risks
There are no risks involved.
Gustav Mahlerlaan 3004
1081 LA Amsterdam
NL
Gustav Mahlerlaan 3004
1081 LA Amsterdam
NL
Listed location countries
Age
Inclusion criteria
* * 18 years - 35 years * minimum of 20 natural teeth * Non-smokers * Organoleptic mean score of minimum 2
Exclusion criteria
* Open active caries * absence of probing depth * 5mm probing and attachment loss * 2 mm * the absence of pregnancy- breastfeeding and systemic diseases * On medications which can cause malodour * the absence of antibiotic in the last 2 months * participation in a clinical study within the previous 30 days * Ongoing dental treatment or any other medical treatment of the oral cavity
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL34505.018.11 |
| OMON | NL-OMON24468 |