The aim of this study is to develop a new model to assess cardiorespiratory fitness of a subject without the need of a standardized laboratory bound protocol and without the need of maximal exertion. The model will be based on daily life…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
niet-klinisch onderzoek met gezonde proefpersonen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
• Maximal aerobic capacity (VO2max) as a measure of cardiorespiratory fitness
as assessed by an incremental test on a bicycle ergometer.
• Maximal aerobic capacity (VO2max) as a measure of cardiorespiratory fitness
as estimated by a combination of heart rate recording and movement registration
(accelerometry) in daily life.
Secondary outcome
maximal heart rate
resting heart rate
heart rate recovery
daily physical activity (accelerometer counts)
body composition (% fat mass and fat-free mass)
Background summary
The assessment of cardiorespiratory fitness is an important health parameter in
several settings, such as clinical, sports and research. High cardiorespiratory
fitness is associated with a lower risk of developing cardiovascular disease.
The gold standard test to determine cardiorespiratory fitness is maximal oxygen
uptake (VO2max) test. This is a test to maximal exertion where the individual
is pushed to reach his/her physiological limit. The measurement of oxygen
uptake requires expensive equipment and supervision. Hence, there are many
sub-maximal exercise protocols to estimate VO2max. In many of these protocols
heart rate (HR) is used to estimate VO2max. However, these tests still require
standardized protocols, often in a laboratory setting. Considering the
importance of cardiorespiratory fitness assessment and the new possibilities
enabled by unobtrusive heart rate monitoring, it is worth investigating the
possibility to assess cardiorespiratory fitness (e.g. VO2max) of a person
without the need of a standardized laboratory bound test and without the need
of maximal exertion.
Study objective
The aim of this study is to develop a new model to assess cardiorespiratory
fitness of a subject without the need of a standardized laboratory bound
protocol and without the need of maximal exertion. The model will be based on
daily life registration of physical activity and heart rate.
Study design
Observational study, methodological study
Study burden and risks
Risks for the participants are minimal since no invasive procedures are
included. The exercise protocol can be easily performed by healthy subjects. To
make sure subjects are allowed to perform a maximal exertion test, potential
participants will be screened using a medical screening questionnaire (see
appendix F1). The maximal exertion test will be conducted by an experienced
operator and a direct line with the hospital is always available.
High Tech Campus 34
Eindhoven 5656 AE
NL
High Tech Campus 34
Eindhoven 5656 AE
NL
Listed location countries
Age
Inclusion criteria
Men and women
Aged between 18-45 years
Body mass index between 18.5-27 kg/m2
Informed consent by the participants
Exclusion criteria
Subjects with a chronic disease, such as chronic obstructive pulmonary disease, diabetes, cardiovascular disease or any condition known to affect normal cardiovascular functioning. Any musculoskeletal condition that would prevent the subject from perfoming the exercise protocol.
Subjects taking medication, except for oral contraceptives.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL41074.068.12 |