Primary objective: To provide a detailed description of the prevalence and cognitive characteristics of navigation impairment in stroke patientsSecondary objectives: To increase knowledge about the neuroanatomical correlates of navigation ability…
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
questionnaire scores
cognitive task battery scores
lesion location
Secondary outcome
n.a.
Background summary
When one is not able to navigate properly, this can have a severe impact on
one*s autonomy and psychosocial wellbeing. A pilot study indicates that
approximately 25 % of stroke patients report such navigation problems. However,
little is known about the nature of these problems. It is well known that
navigation consists of a number of components, such as recognition, temporal
order memory, and sense of direction. However, it is not known which of these
neuropsychological components are most often affected in stroke patients, what
the neuroanatomical correlates of these components are, and how navigation
impairment affects quality of life of stroke patients. The proposed study is
aimed at providing a detailed description of the prevalence and cognitive
characteristics of navigation impairment in a large sample of stroke patients.
Study objective
Primary objective: To provide a detailed description of the prevalence and
cognitive characteristics of navigation impairment in stroke patients
Secondary objectives: To increase knowledge about the neuroanatomical
correlates of navigation ability and about relationships between navigation
ability and quality of life in stroke patients.
Study design
A large sample of stroke patients will fill out self-reported measures of
navigation, quality of life, cognitive functioning, mobility, and anxiety and
depression. The patients who score below the cut-off for navigation ability and
a subset of the patients who do not show navigation problems on this
questionnaire will be included into a behavioural test battery. In this
session, all main aspects of navigation ability will be tested with a computer
task that includes virtual environments. The session also includes a similar
navigation task in a real environment, along with a set of standardized
neuropsychological tests.
Study burden and risks
The risks are assumed to be negligible. The burden is kept to a minimum
Heidelberglaan 2
Utrecht 3584 CS
NL
Heidelberglaan 2
Utrecht 3584 CS
NL
Listed location countries
Age
Inclusion criteria
Stroke, 18 years of age or older, six months or longer after stroke, living at home after rehabilitation (inpatient or outpatient) at rehabilitation centre De Hoogstraat, no severe mobility problems, ability to walk or bike outside without supervision, lesions are visible on a CT or MRI scan, written informed consent is provided
Exclusion criteria
Not being able to communicate in Dutch or severe global aphasia (exclusion if SAN score < 5), history of psychiatric disorders or substance abuse
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL40322.041.12 |