The main aim of this study is to explore the recovery of physical and psychological health status, and HRQoL simultaneously in lung cancer patients that have undergone lung resection in the Netherlands. Next to that, we hope to identify theā¦
ID
Source
Brief title
Condition
- Respiratory and mediastinal neoplasms malignant and unspecified
- Respiratory tract neoplasms
- Respiratory tract therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome measures of this study are:
- Exercise capacity (VO2peak with maximal cycle test (CPET))
- Distress (HADS)
- Physical Functioning subscale of the EORTC C30
Secondary outcome
Lung functioning (total spirometry)
Quality of Life (EORTC C30 and LC13)
Physical functioning (6MWT and 30 seconds Chair Stand Test)
Pain (BPI )
Fatigue (MFI)
Self-efficacy (SES)
Coping strategies (MAC)
Daily physical activity patterns(accelerometer and IPAQ)
Disabilities and Participation (Last-meter)
Healthcare use
Healthcare need
Background summary
Although lung resection is the preferred treatment for early-stage lung cancer,
it causes a considerable decay of physical health, Health-Related Quality of
Life (HRQoL), and psychological functioning. Prospective studies in lung cancer
patients treated with lung resection, mainly focused on the recovery of
physical health (such as lung function and exercise capacity), and HRQoL.
However, these outcome measures have been measured largely independent from
each other. Furthermore, recovery may further be complicated by psychological
symptoms. So far, little evidence from prospective studies is available to
clarify the prevalence and development of psychological distress following lung
resection. Lastly, it is unknown whether lung cancer patients treated with lung
resection feel the need for post-surgery rehabilitation. Hence, there is a need
for studies with a more holistic approach in which the recovery of physical and
psychological health status, and HRQoL after lung resection is explored
simultaneously, and tested multiple times following surgery. Also, we believe
that it is necessary to assess perceived *healthcare need* in this specific
population. These insights can be used for the future optimization of
rehabilitation programs for lung cancer patients treated with lung resection.
Study objective
The main aim of this study is to explore the recovery of physical and
psychological health status, and HRQoL simultaneously in lung cancer patients
that have undergone lung resection in the Netherlands. Next to that, we hope to
identify the perceived need for rehabilitation.
Study design
A prospective cohort study will be performed to answer the research questions.
Study burden and risks
The risks associated with participation in the study are considered small.
Patients will receive regular care complemented with several questionnaires,
interviews, activity monitoring and easy to perform physical performance tests.
The activity monitor will cause no restriction on daily activity performance.
The physical performance test, such as the 6MWT and the 30-CST, are executed at
their own pace and heart rate is monitored continuously during the 6MWT.
Although the cardiopulmonary exercise test (CPET) pushes the patients to their
maximal cardiopulmonary level, only patients that are approved by their lung
physician or lung surgeon will be tested. Furthermore, this test will be
executed by trained personal, heart functioning will be monitored during
testing, and testing is stopped by signs of symptoms.
Roessinghsbleekweg 33b
7522 AH Enschede
NL
Roessinghsbleekweg 33b
7522 AH Enschede
NL
Listed location countries
Age
Inclusion criteria
a) Age 18 * 80 years;
b) Histologically confirmed or suspected lung cancer;
c) Scheduled or on waiting list for lung resection with curative intention.
Exclusion criteria
a) Not able to perform basic skills like sitting, lying down or walking;
b) Cognitive disorders not cancer-related;
c) Severe emotional instability which will hamper study participation;
d) Uncontrolled cardiovascular and/or neurological disease;
e) Not able to understand Dutch or English (written and/or verbal);
f) Palliative treatment.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL38848.031.11 |