Objective: To assess the effect of beer consumption, with a range of alcohol content, on fluid balance after exercise-induced dehydration. Hypothesis: Based on the glucose and electrolyte composition of beer, and the blurred effect of alcohol in the…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
dehydratie (na inspanning)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter will be fluid balance. This will be determined by
measuring urine production up to five hours after post-exercise rehydration
(t=0,1,2,3,5 hours).
Secondary outcome
Urine samples will be analysed for osmolality and sodium and potassium content.
Body composition (total body water) will be assessed by Bio-Impedance Analysis
(BIA/BIS), immediately after exercise and at 2 and 5 hours after the start of
rehydration.
For safety purposes, breath alcohol concentration will be assessed up to five
hours after post-exercise rehydration (t=0,1,2,3,5 hours). In addition, this
assessment will give an indication of the velocity of alcohol degradation by
the dehydrated body.
Background summary
Adequate rehydration after endurance exercise is important. Among amateur
team-based sports, it is common to drink moderate to large amounts of alcoholic
beverages, mainly beer, after training or competition. Alcohol is known to
increase urine output, which could interfere with adequate rehydration after
exercise. It is suggested the diuretic effect of alcohol is blurred when the
body is dehydrated. Moreover, rehydration drinks typically consist of water,
carbohydrates and electrolytes, i.e. sodium. Beer contains - besides alcohol -
water, carbohydrates and a small amount of electrolytes. The final consequences
for rehydration and fluid balance after exercise for beer with different
alcohol contents are not completely clear. Therefore, the objective of this
proposal is to assess the effect of beer consumption, with a range of alcohol
content, on fluid balance after exercise-induced dehydration. The rehydration
capacity of these beverages is compared with a rehydration drink.
Study objective
Objective: To assess the effect of beer consumption, with a range of alcohol
content, on fluid balance after exercise-induced dehydration.
Hypothesis: Based on the glucose and electrolyte composition of beer, and the
blurred effect of alcohol in the dehydrated state, it is expected that
non-alcoholic and low-alcohol beer result in a comparable fluid balance as a
hypotonic glucose-electrolyte rehydration drink, while lager beer (5% alcohol)
is associated with an increased urine production and a retarded rehydration,
like water.
Study design
Cross-over intervention trial.
Intervention
Participants will receive five test-drinks in a random order: beer (lager),
low-alcohol beer, non-alcoholic beer, water and rehydration drink. At least 7
days will be considered between test days.
Study burden and risks
There are minor risks for the participants during this study. Subjects are only
mildly dehydrated and receive drinks, equal to their fluid loss directly after
exercise. A maximum amount of three alcoholic beverages will be provided during
each condition. Participants are not allowed to leave the research facilities
until the breath alcohol test is within the accepted range (i,e 0,22 mg/L
expired air, ~0,5 °/°°). The exercise test will result in fatigue, and can give
rise to some muscle soreness afterwards. All functional measurements (urine
volume, urine osmolality, body weight, body composition (BIA/BIS) and breath
alcohol concentration) are non-invasive and risks are therefore minimal.
Subjects have to adhere to specific guidelines one day before every test
(standardized diet, no physical activity, overnight fast, no alcohol
consumption, drinking at least 2 liters of fluid) and have to fill out a
questionnaire for screening purposes. There is no direct (health-related)
benefit for the participant. The time investment requested from the
participants excluding travel time is in total 37 hours for 6 visits and
screening.
Participants that complete the study will receive ¤ 180.
Postbus 8129
6700 EV Wageningen
NL
Postbus 8129
6700 EV Wageningen
NL
Listed location countries
Age
Inclusion criteria
• Age between 18-35 yrs
• Male gender
• Performing sports 1-4 times a week
• Normal BMI (20-25 kg/m2)
• Body weight 70-80kg.
• Healthy (no medication use)
• Used to drink beer.
• No family history of alcoholism.
Exclusion criteria
Unable to perform exercise
- Drinking more than 14 alcoholic beverages a week
- Use of drugs
- Medication use
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL39718.081.12 |