To test the age by stress interaction model by investigating how aging alters neural responses to environmental stress.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Gezonde deelnemers
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Functional Magnetic Resonance Imaging (fMRI)
Secondary outcome
• Salivary levels of cortisol and alpha-amylase
• Self-report questionnaires
• Psychophysiological recordings (heart rate, blood pressure)
Background summary
Older adults show less effect of negative stressors on emotion regulation and
emotional memory, in spite of a high prevalence of mood and anxiety disorders
in late life.
Study objective
To test the age by stress interaction model by investigating how aging alters
neural responses to environmental stress.
Study design
A counterbalanced, factorial, crossover design.
Study burden and risks
The risk associated with participation can be considered negligible and the
burden can be considered minimal. No pharmacological or (otherwise) invasive
interventions are applied. Participants will undergo non-invasive medical
screening as well as two MRI sessions.
Geert Grooteplein 21
Nijmegen 6525 EZ
NL
Geert Grooteplein 21
Nijmegen 6525 EZ
NL
Listed location countries
Age
Inclusion criteria
Male, between 60 and 75 years of age, predominant right-handedness
Exclusion criteria
History of psychiatric treatment or current psychiatric treatment, history of neurological treatment or current neurological treatment, history of endocrine treatment or current endocrine treatment.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39850.091.12 |