The research aims to identify avoidable and non-preventable factors, which contribute to the development of chronic tophaceous gout. In addition, the study aims to assess the consequences (quality of life, comorbidity) of tophi.
ID
Source
Brief title
Condition
- Purine and pyrimidine metabolism disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main outcome measure is the state tophaceous vs. non- tophaceous gout, and
the main parameters are the avoidable and unavoidable factors which contribute
to the emergence of tophaceous gout.
Secondary outcome
not applicable
Background summary
Hyperuricemia is one of the most important etiological factors in the etiology
of gout. Acute gout can develop into chronic tophaceous gout after persistent
high levels of uric acid. The disease burden of chronic tophaceous gout is
substantial. Although hyperuricemia is easily treated with medication and/or
lifestyle advice and although chronic tophaceous gout is largely preventable,
patients with this stadium of gout are often seen in clinical practice.
Study objective
The research aims to identify avoidable and non-preventable factors, which
contribute to the development of chronic tophaceous gout. In addition, the
study aims to assess the consequences (quality of life, comorbidity) of tophi.
Study design
The study has a retrospective cohort and cross-sectional study design by means
of status, questionnaires and an interview with gout patients.
Study burden and risks
There are no benefits or risks for the participants, ie there are no invasive
acts. Participants will visit the rheumatology clinic and fill in a number of
questionnaires. Overall, this visit has a duration of 75 minutes.
P. Debyelaan 25
6229 HX Maastricht
NL
P. Debyelaan 25
6229 HX Maastricht
NL
Listed location countries
Age
Inclusion criteria
by a rheumatologist confirmed diagnosis of gout during the period 1-1-2010 to 1-4-2012
18 years or older
signation informed consent
Exclusion criteria
not being able to read and understand the Dutch language
incompetent
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39525.068.12 |