2. OBJECTIVESPrimary Objective: 1. Does conversion tremor show similar abnormal cerebral activation patterns compared to conversion pareses?Secondary Objective:1. Is decreased precuneus activity also present in conversion tremor?
ID
Source
Brief title
Condition
- Movement disorders (incl parkinsonism)
- Somatic symptom and related disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
fMRI data: differences in cerebral activation recorded by 3T fMRI
Secondary outcome
NA
Background summary
Conversion tremor is a form of conversion disorder as defined by DSM-IV-TR
criteria. Symptoms suggest a medical condition and are associated with
psychological factors. The symptom is not intentionally produced. It is well
documented that psychogenic symptoms are accompanied by a high incidence of
psychological symptoms and insufficient use of active coping strategies (M.
Beilen van, Griffioen, & Leenders, 2009).
Previous research suggests that decreased activity in the precuneus and
supramarginal gyrus are typical for conversion disorder (M. Beilen van, De
Jong, Laar, Gieteling, & Leenders, 2011). We hypothesized that the precuneus
abnormality reflects a general deficit in all types of conversion disorder .
This is the first time that two types of conversion symptoms are compared using
fMRI.
Study objective
2. OBJECTIVES
Primary Objective:
1. Does conversion tremor show similar abnormal cerebral activation patterns
compared to conversion pareses?
Secondary Objective:
1. Is decreased precuneus activity also present in conversion tremor?
Study design
Between-subject comparison
Study burden and risks
NA
postbus 30.001 ab51
Groningen 9700 RB
NL
postbus 30.001 ab51
Groningen 9700 RB
NL
Listed location countries
Age
Inclusion criteria
1. conversion tremor in one hand/ or one arm including the hand, with normal opposite limb functioning, or, conversion paresis in one hand/ or one arm including the hand, with normal opposite limb functioning.
2. symptoms present for at least 4 weeks before approaching the patient about the study
3. between 18 to 75 years old
Exclusion criteria
1. Severe psychiatric disturbance such as psychosis, or incapability of making personal decisions about participation in the study for other reasons, as defined by a psychiatrist.
2. Epilepsy in the medical history
3. Pregnancy
4. Tattoo*s including red colour
5. Pace-maker, medication pumps
6. Other metal inside the body
7. Claustrofobia
8. Poor general health
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL38457.042.11 |