To investigate differences in clinical outcome between patients with lytic spondylolisthesis and residual hernia surgery pain undergoing minimal invasive spinal fusion surgery. Beside this clinical outcome we investigate the radiological outcome of…
ID
Source
Brief title
Condition
- Tendon, ligament and cartilage disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Is the outcome of patients undergoing 1- or 2-level posterior lumbar interbody
fusion in combination with minimally invasive pedicle screw placement
(MIP-PLIF technique) the same for patients who had residual hernia surgery pain
as for patients with lytic spondylolisthesis?
Secondary outcome
Does significant subsidence of the cage occur two years after surgery in these
80
patients? If there is significant subsidence, is there a significant difference
between the groups?
Background summary
Minimally invasive lumbar fusion surgery is in his infancy. Magerl first
reported the use of percutaneous pedicle screws for spinal fusion in 1982.
Foley et al subsequently advanced the design of percutaneous pedicle screws,
combined with the tubular retractor system. This led to the development of
minimally invasive percutaneous posterior lumbar interbody fusion (MIP-PLIF).
The first MIP-PLIF using the Sextant system (Medtronic) was performed in 2001
(7). The first results of this new technique are promising and in our hospital
we have performed lumbar fusion with the Sextant system in over 300 patients
with lytic spondylolisthesis and patients with recurrent radiculopathy after
hernia surgery. Our experience is that patients with a lytic spondylolisthesis
undergoing minimally invasive interbody fusion have a better outcome than
patients with recurrent radiculopathy after hernia surgery. To our knowledge
there is no study comparing the outcome of lumbar fusion surgery in these
patient groups.
Study objective
To investigate differences in clinical outcome between patients with lytic
spondylolisthesis and residual hernia surgery pain undergoing minimal invasive
spinal fusion surgery. Beside this clinical outcome we investigate the
radiological outcome of the lumbar fusions.
Study design
Retrospective study with prospective follow-up. Two cohorts of an equal number
of 40 patients. One cohort with diagnosis lytic spondylolisthesis and one with
diagnosis recurrent radiculopathy after hernia surgery. All 80 patients
underwent 1-level or 2-level lumbar spine fusion in our hospital between 2002
and 2010, using the MIP-PLIF technique (Sextant system, Medtronic). The cohorts
will be matched for age, gender and follow-up time. Data will be collected
after a minimal follow-up time of two years after surgery. Enrolment criteria
included available demographic, surgical and clinical outcome data.
Study burden and risks
One single X-ray. (X lumbal spine lateral)
Hilvarenbeekseweg 60
5022 GC Tilburg
NL
Hilvarenbeekseweg 60
5022 GC Tilburg
NL
Listed location countries
Age
Inclusion criteria
Adults (>18 yrs)
Patients who underwent 1-level or 2-level lumbar spine fusion with new sextant technique (performed in St Elisabeth hospital between 2002 and 2010)
Exclusion criteria
No spondylodesis prior to the spinal fusion with sextant technique
Age <18 yrs
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL38113.008.11 |