The identify the health-related quality of life of elderly patients with resected stage III colon cancer and relate the outcomes to patient and treatment characteristics (surgery alone or surgery plus adjuvant chemotherapy). Furthermore, the impact…
ID
Source
Brief title
Condition
- Gastrointestinal neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Health-related quality of life
Secondary outcome
Neuropathy
Anxiety
Depression
Fatigue
Background summary
The number of elderly patients with stage III colon cancer is substantial and
rising. According to the Dutch guideline, these patients should be treated with
adjuvant chemotherapy after resection of the primary tumour. However, in daily
practice a large proportion of these elderly patients does not receive this
treatment. The efficacy of adjuvant chemotherapy on disease-free and overall
survival has been established in clinical trials. However, the impact of
adjuvant chemotherapy on health-related quality of life is unknown.
Study objective
The identify the health-related quality of life of elderly patients with
resected stage III colon cancer and relate the outcomes to patient and
treatment characteristics (surgery alone or surgery plus adjuvant
chemotherapy). Furthermore, the impact of adjuvant chemotherapy on neuropathy,
anxiety, depression and fatigue will also be measured.
Study design
A population-based, longitudinal study, including patients immediately after
surgery and following them for 12 months.
Study burden and risks
Participation does not pose a risk to the patient. The patient can avoid
possible psychological burden by not completing the questionnaire.
Zernikestraat 29
Eindhoven 5612HZ
NL
Zernikestraat 29
Eindhoven 5612HZ
NL
Listed location countries
Age
Inclusion criteria
Diagnosed with primary colon cancer
TNM stage III (T1-4 N1-2 M0)
Age at time of diagnosis 70 years or older
Able to complete a Dutch questionnaire
Exclusion criteria
Patients who are not able to read or write Dutch
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL42739.015.12 |