To identify predictors for the different treatment options for obesity (1. combined lifestyl intervention plus, 2. E-health treatment, 3. bariatric surgery; inclusion for treatment options 1 and 2 takes place in the EMC, inclusion for the treatment…
ID
Source
Brief title
Condition
- Metabolism disorders NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To creat a databank with data about weight loss and
metabolic/endocrine/immunological parameters collected before the start of
treatment, 10 weeks after treatment and 1.5 years after treatment to develop
personalized treatment modalities
Secondary outcome
-
Background summary
Obesity is an important medical problem. The percentage of adults (older than
20 years of age) with overweight worldwide was 47.9%, of these adults 12% was
obese. Overweight is a riskfactor for the developemnt of multiple associated
diseases. This result in higher health risks in these patients and thus higher
medical costs. Current treatment modalities for obesity do not always result in
long term weight loss. Treatment of obesity is complex and deseves a
multidisciplinary approach. Therefore a multidisciplinary center for the
treatment of obesity was established in the Erasmus Medical Center (EMC) and
the Sint Fransiscus Gasthuis (SFG). In this center innovative treatment
modalities are developed for the treatment of obesity.
Study objective
To identify predictors for the different treatment options for obesity (1.
combined lifestyl intervention plus, 2. E-health treatment, 3. bariatric
surgery; inclusion for treatment options 1 and 2 takes place in the EMC,
inclusion for the treatment options 3 takes place in the SFG)
Study design
prospective observational study, create a databank
Study burden and risks
Patients do not benefit from participation in the study. During regular
treatment, minimally invasive procedures with low risks for the patients will
be performed to collect extra data for the databank. These procedures include
questionnaires, collection of extra blood, collection of saliva and some hairs.
Kleiweg 500
Rotterdam 3045PM
NL
Kleiweg 500
Rotterdam 3045PM
NL
Listed location countries
Age
Inclusion criteria
adults with a BMI > 35 kg/m2 with comorbidities or a BMI > 40 kg/m2;Co-morbidities:
• Diabetes mellitus type 2
• Insuline resistance (defined by the HOMA-index, based on insulin/glucose ratio)
• Dyslipidaemia
• Hypertension
• Artrosis
• Sleep-apnoea syndrome
• Steatosis, steatohepatitis
• Polycystic Ovary Syndrome
Exclusion criteria
No understanding ofDutch language
intelectual disability (IQ < 80)
treatable cause of obesity
no motivation to participate in study
Psychopathology needing different treatment modalities
pregnancy
High risk anaesthesia
serious eating disorder
Active gastro-intestinal disease
alcohol or drugs abusus
Length of hear less than 3cm
Revision of earlier bariatric surgery
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL49332.101.15 |