The objective of this study is to determine the light and dark adapation time and contrast sensitivity in changing background light conditions.
ID
Source
Brief title
Condition
- Glaucoma and ocular hypertension
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Measurement of (1) the light- and dark adapation and (2) the contrast
sensitivity in changing background light conditions.
Secondary outcome
N/A
Background summary
Many patients with glaucoma experience difficulties when going form light to
dark and vice versa. These difficulties are not only present in patients with
severe glaucoma, but also in patients with a normal visus and an intact visual
field.
We already researched the influence of light- and darkadaptation using a
questionnaire (METc 2014/338) and confirmed the difficulties described above.
In addition, patients with glaucoma experience longer adaptation times compared
with healthy subjects. In a former project (METc 2014/409) we researched the
influence of static light conditions. Now we continue with dynamic light
conditions.
Study objective
The objective of this study is to determine the light and dark adapation time
and contrast sensitivity in changing background light conditions.
Study design
Case-control study.
Study burden and risks
A single visit, in which the light and dark adaptation time and the contrast
sensitivity in changing background light conditions will be measured. In
addition, letters will be read in the standardized light conditions. For
healthy subjects there are few extra tests to check the healthy state of the
eye. Total time invested is 1.5 to 2 hours. In healthy subjects, it is possible
that an eye disease is discovered during the course of this study. The
resulting psychological stress to the subject can be a disadvantage. However,
the advantage is an early start of adequate treatment. All measurements are
conducted using optical techniques that do not touch the eye and therefore are
completely harmless. There is no risk during the experiments. No mydriasis
(pupil dilation) will be implemented.
Hanzeplein 1
Groningen 9700 RB
NL
Hanzeplein 1
Groningen 9700 RB
NL
Listed location countries
Age
Inclusion criteria
Glaucoma patients aged 40-70 years who visit the ophthalmology outpatient department of the UMCG, provide written informed consent form and meet the inclusion- exclusion criteria. ;Healthy subjects will consist of people who have signed in, without ophthalmic abnormalities and provide written informed consent.
Exclusion criteria
Glaucoma patients:
- Visual acuity below 1.0 (below 50 years of age) or below 0.8 (above 50 years).
- Visual field defects not caused by glaucoma;Healthy subjects:
- Visual acuity below 1.0 (below 50 years of age) or below 0.8 (above 50 years).
- Visual field defects which are not understood.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL54016.042.15 |