To obtain insight into the age-specific seroprevalence (immunity) for diseases included in the NIP of the Dutch general population.
ID
Source
Brief title
Condition
- Hepatobiliary neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The age-specific seroprevalence (immunity) for diseases included in the NIP of
the Dutch general population.
Secondary outcome
The age-specific seroprevalence against other infectious diseases, in
particular those that might be vaccine-preventable in the near future and
against those diseases with a frequent subclinical course.
By collecting additional samples, the relationship between immune status and
carriage of potential pathogens, lifestyle factors and environmental factors
can be studied.
Background summary
Measuring the serological effects of the different vaccinations (immune
surveillance) is an important tool for the evaluation of the National
Immunisation Programme (NIP) by providing insight in the immune status of the
population, by identifying possible gaps in the immunity and subpopulations at
risk and by assessing (re) emergence of disease.
Study objective
To obtain insight into the age-specific seroprevalence (immunity) for diseases
included in the NIP of the Dutch general population.
Study design
This study is an observational study with a single invasive measurement
(drawing of blood) and non-invasive measurement (saliva). For a subgroup,
optional, a nose and throat swab will be collected as well as a faecal sample.
Study burden and risks
Discomfort from blood collection is present and is considered a minimal burden.
If invitee agrees to participate in the optional additional investigations
there will be discomfort for a short duration during the swabs of the nose and
throat. The study is a cross-sectional study and aims to be representative of
the Dutch population. The primary endpoint is the evaluation of the NIP.
Therefore the age groups under 5 years are of special interest and cannot be
excluded from this study. The questionnaire contains several questions about
health perception, diseases and vaccination data but also some more personal
questions regarding sexual behaviour and sexual transmitted diseases are asked.
The participant is free to answer or to skip these personal questions.
Antonie van Leeuwenhoeklaan 9
Bilthoven 3721 MA
NL
Antonie van Leeuwenhoeklaan 9
Bilthoven 3721 MA
NL
Listed location countries
Age
Inclusion criteria
* Subject is part of the study sample, aged 0 to 89 years old and has received a personal invitation for the PIENTER3 study.
* Subject has given written Informed Consent (IC) before the start of the study visit.
Exclusion criteria
None
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL54228.094.15 |