The proposed project will examine the potential benefit of adding iABM to TAU for AUD and CUD patients in GB-GGZ addiction care on the health outcomes related to the increase in costs for adding this intervention to treatment as usual. Therefore,…
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Brief title
Condition
- Other condition
Synonym
Health condition
verslaving
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome parameters are changes in substance use, level of dependency
and craving, and relapse-rates. Health condition, and societal costs will be
primary outcome parameters to assess cost-effectiveness of this intervention.
Secondary outcome
The secondary outcome parameters are attentional bias, and secondary physical
and psychological complaints (and specifically anxiety, depression and stress).
Further outcome parameters are subjective evaluations of the training, from the
perspectives of both patient and therapist.
Lastly we would like to analyze for whom this training worked and for whom it
did not work (with independent variables such as co-occurring diagnoses, length
of addiction period, number of sessions that were completed, motivation for
treatment (number of no-shows)).
Background summary
Addiction is characterized by high relapse numbers after successful treatment.
Cognitive models of addiction suppose that the development and maintenance of
addiction can be explained by an imbalance between automatic, impulsive
processes and reflective, controlling processes. Research has shown that
addicted individuals demonstrate a heightened automatic attention (attentional
bias, AB) for *their* substance. That is, their attention is automatically and
unintentionally drawn towards information that is related to their addiction,
and they have trouble redirecting their attention away from this information.
Using computer tasks the strength of this AB can be measured. stronger AB has
been associated with greater severity of addiction, poorer treatment outcomes,
and increased relapse.
Recently, new techniques have been developed in order to train the automatic
attention away from substance information (attentional bias modification, ABM).
Importantly, ABM can be effectively delivered via the Internet (iABM), which
allows a low-cost, efficient delivery system for this treatment. The proposed
project will investigate the (cost)effectiveness of iABM as an add-on to
addiction treatment as usual (TAU) (i.e., blended therapy).
We hypothesize that patients receiving iABM as add-on to TAU, will show
less addiction problems, decreased relapse, increased health, reduced physical
and psychological complaints, and reduced use of health care post-intervention
and at 6 & 12 month FU. Further, we hypothesize that the effects on the
individual and societal level cause a decrease in societal costs that outweighs
the additional costs of the iABM.
Study objective
The proposed project will examine the potential benefit of adding iABM to TAU
for AUD and CUD patients in GB-GGZ addiction care on the health outcomes
related to the increase in costs for adding this intervention to treatment as
usual. Therefore, the project was designed to examine the following questions:
1- Does adding iABM to TAU for AUD and CUD patients at GB-GGZ lead to a more
sustained decrease in addiction problems as reflected by lower
post-intervention, and 6 & 12 month level of substance use, dependency, craving
and relapse rates?
2- Does adding iABM to TAU for AUD and CUD patients at GB-GGZ enhance their
broader health, and reduce their use of other health care resources at 6 & 12
month follow-up?
3- Do the economic benefits of adding iABM to TAU at GB-GGZ outweigh the costs?
A secondary aim of this project is to explore which type of patients benefit
most from the addition of internet-based ABM, in order to enable the most
effective targeted delivery of this treatment component in the future.
Study design
In an RCT study with pre- post- design and 6 & 12-month FU, patients will be
assigned to TAU+iABM condition, or control condition (half TAU+placebo iABM,
half TAU only).
Intervention
The iABM is a computerized intervention aimed at modifying automatically
triggered attentional processes that have been shown to play a role in
addiction During this intervention patients will be shown moving images of
alcohol (cannabis) on a computerscreen, together with neutral moving images.
They are instructed to follow the neutral images with the cursor of the mouse,
and thus, to neglect the alcohol (cannabis) images. The iABM will be delivered
at home, in multiple sessions concurrent with and for the duration of TAU.
Study burden and risks
We expect a direct and longer-term benefit for the iABM group on top of effects
of TAU (and to a lesser extent for the placebo training group), related to a
small investment (short sessions, at home environment), and a very limited
(possibly even absent) risk (no extra travels, no medication, possible (short)
increase of craving by demonstration of pictures of alcohol and cannabis, but
certainly not stronger triggers than the 'daily life' triggers. Further, we
expect no extra benefit on top of TAU for the control group, related to a
minimum investment of four times a 20-30 minute assessment, and no potential
risk factors.
Leonard Springerlaan 27
Groningen 9727 KB
NL
Leonard Springerlaan 27
Groningen 9727 KB
NL
Listed location countries
Age
Inclusion criteria
included will be: individuals diagnosed with alcohol use disorder (AUD) and/or cannabis use disorder (CUD), who start basis GGZ treatment in one of the three participating addiction treatment centers
Exclusion criteria
Patients showing compulsive gaming, a gambling disorder, or internet addiction will be excluded from participation because the internet delivered training task might have counterproductive effects for this group of patients. Further, patients who do not have a Personal Computer (PC), or Notebook and access to internet at home will be excluded for this study.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL54435.042.15 |