Curcumin study: Plasma concentrations of curcumin, piperin and genistein in subjects using over the counter supplements

The interest in curcumin is growing and despite all the pre-clinical evidence
the effectiveness in clinical trials is very limited. The food supplements with
curcumin currently on the market as over the counter products are accompanied
with large advertisements and probably fallacious claims about the
bioavailability. The costs for these products are high and a price of 40-50
euros for one bottle is not uncommon. Despite all this patients are currently
using this supplement as additional care.
In this pilot research we want to investigate which products, formulations and
dosages patients use. We want to measure the plasma levels reached during
intake of these food supplements. We also want to have more inside in the
different food supplements patients use such as piperin and genistein.

The aim of this study is to investigate if curcumin is detectable when subjects
use curcumin supplements in daily life.

This is a study into curcumin food supplements taken by subjects in daily life.
In which we aim to include 50 subjects.

The interventions in this study are:
• One questionnaire about the food supplement use by subjects
• Two blood samples will be collected, one before intake of their food
supplement with curcumin and one after intake of the food supplement.

In this study no product is involved as intervention or additional to their
daily routine. The only intervention that the including adult subject will
undergo is a two times sampling of their blood and completion of a
questionnaire.