The aim of this study is to evaluate the long-term imaging and functional outcomes of overuse injuries of the wrist in (former) athletes.
ID
Source
Brief title
Condition
- Joint disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Prevalence of signs of degenerative disease of the previously injured wrist
joint on conventional posterior-anterior, *, and lateral radiographs, assessed
using the osteoarthritis score developed by Kellgren and Lawrence.
Secondary outcome
Multiple functional outcome measures will be used. Patient-rated outcome
measures include:
- Functioning of the upper extremities measured by the Dutch validated version
of the Disability of the Arm, Shoulder and Hand (DASH) questionnaire;
- Functioning of the hands and wrists measured by the Dutch validated version
of the Patient-Rated Wrist and Hand Evaluation (PRWHE-DLV);
- Functioning in relation to work, measured by the newly developed WORQ-UP
questionnaire that is currently being validated, and by questions about work
ability in relation to both wrists separately.
Other outcome measures include:
- Isometric hand grip strength of the hand on the previously injured side
measured using a Jamar dynamometer compared to the non-injured side, and
compared to normative population data;
- Kellgren and Lawrence osteoarthritis score on conventional radiographs of the
overuse-injured wrist at follow-up, compared to the Kellgren and Lawrence
osteoarthritis score of the non-injured wrist at follow-up, both assessed by a
specialized musculoskeletal radiologist and/or a musculoskeletal radiology
resident;
- Abnormalities and Kellgren and Lawrence osteoarthritis score on conventional
radiographs of the affected wrist compared to wrist imaging at first hospital
visit, assessed by a specialized musculoskeletal radiologist and/or a
musculoskeletal radiology resident;
- Demographic and anthropomorphic characteristics (e.g. age, length in
centimetres, weight in kilograms) and training characteristics (e.g. starting
age, level, training intensity in hours, training frequency in days, specialty
elements) of participants.
- Work characteristics (e.g. type of work, work hours, education) of
participants.
Background summary
In clinical practice, overuse injuries of the wrist are frequently seen in
young athletes. Possible long-term complications of overuse injuries of the
wrist include degenerative conditions of the wrist such as osteoarthritis,
which can present with bothersome symptoms. However, the prevalence of these
long-term outcomes of overuse wrist injuries as well as the consequences on
functioning in daily life, sports and work, have not been investigated
systematically. The growing number of young athletes at risk for overuse
injuries of the wrist, and with many prospective years of active participation
in the employment market, has raised awareness of the essential need for
evaluation of the long-term consequences of these injuries. More insight in the
functional consequences on (former) athletes* daily life, work and sports can
be valuable for the improvement of treatment, return-to-play counseling, and
targeted secondary prevention strategies.
Study objective
The aim of this study is to evaluate the long-term imaging and functional
outcomes of overuse injuries of the wrist in (former) athletes.
Study design
Cohort study taking place in one specialized centre.
Study burden and risks
If patients agree to participate, they will be invited for a one-time visit to
the AMC. During this visit, they will be asked to fill out a questionnaire
containing functional outcome measures such as the Disability of the Hand,
Shoulder and Wrist (DASH) questionnaire and the Patient-Rated Wrist and Hand
Evaluation (PRWHE). Subsequently, hand grip strength of both hands will be
assessed using a Jamar dynamometer in three separate measurements per hand.
Lastly, conventional radiographs of both wrists will be made, with a total
radiation burden of 0.006 mSv. There are no AEs, SAEs or SUSARs expected since
and the radiation dose is minimal and no intervention is applied. Moreover, no
additional benefit of harm is expected in the course of this study that could
lead to premature termination of the study.
Meibergdreef 9
Amsterdam 1105 AZ
NL
Meibergdreef 9
Amsterdam 1105 AZ
NL
Listed location countries
Age
Inclusion criteria
- Any diagnosis of overuse injury of the wrist, defined as a stress fracture or other stress reaction or soft tissue irritation, with no history of trauma, based on clinical assessment and/or imaging;
- No history of overuse injury of the contralateral wrist, according to same criteria as above, based on patient history and patient records;
- Active participation in a wrist-loading focus sport (gymnastics, tennis, judo, field hockey, volleyball, and rowing) or other sport that requires repetitive loading of the wrist at time of diagnosis of overuse wrist injury;
- Age * 25 years at moment of diagnosis of overuse injury of the wrist;
- No history of trauma or overuse injury of the contralateral wrist;
- No surgical treatment of the overuse injury of the wrist;
- No neurovascular disorders (e.g. Raynaud syndrome) or systemic diseases (e.g. diabetes mellitus, rheumatoid arthritis) affecting the musculoskeletal system;
- No other trauma of the wrist after the diagnosed overuse injury of the wrist that now predominantly causes symptoms and/or limitations of the upper extremity;
- No other conditions that cause symptoms or limitations of the upper extremity;
- Not pregnant.
Exclusion criteria
See inclusion criteria
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL59098.018.16 |