1. To investigate short- as well as long-term outcomes in patients who underwent CAWR in the Academic Medical Center and St Marks Hospital London between 2004 and 2015 with hernia recurrence as primary outcome. Secondary outcomes involve morbidity,…
ID
Source
Brief title
Condition
- Abdominal hernias and other abdominal wall conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Hernia recurrence
Secondary outcome
1. Short-term: Post-operative wound complications, intra-abdominal
complications, medical complications, length of hospital stay, re-operations,
emergency department visits, re-admissions and short-term mortality.
2. Long-term: Bulging, hernia recurrence, occurrence of a parastomal hernia,
fistula formation (recurrence), re-operation for recurrence, scar assessment,
patient satisfaction and long-term mortality.
Background summary
Patients undergoing major complex abdominal wall repair (CAWR) are at high risk
to develop (wound) complications. Long-term results are not well known as most
studies investigate only the short-term results. Moreover, the role of
pre-operative CT-scanning in complex abdominal wall repairs is becoming more
important. The exact role of CT findings in surgery preparation is not known.
Study objective
1. To investigate short- as well as long-term outcomes in patients who
underwent CAWR in the Academic Medical Center and St Marks Hospital London
between 2004 and 2015 with hernia recurrence as primary outcome. Secondary
outcomes involve morbidity, mortality and patient related outcomes.
2. To investigate whether CT derived measurements help to predict what complex
abdominal wall reconstructive techniques are required to repair a given defect
and predict outcome.
Study design
Data on patient characteristics, CT-scan characteristics, operation details and
postoperative data were assessed as retrospective cohort study. Hernia
recurrence on the long-term was measured at one prospective follow-up moment.
Study burden and risks
The risks associated with participating in this study are negligible. We ask
patients* time to visit the outpatient clinic of the AMC once. This
consultation will take approximately 20-30 minutes and involves a short
physical examination, filling out a questionnaire, and taking two photographs
of the abdominal wall.
Meibergdreef 9 G4-132.1
Amsterdam 1105AZ
NL
Meibergdreef 9 G4-132.1
Amsterdam 1105AZ
NL
Listed location countries
Age
Inclusion criteria
- Complex abdominal wall repair in Academic Medical Center Amsterdam or St Marks Hospital London between 2004-2015
- Midline incison
- VHWG grade 3 of 4, modified VHWG grade 3
Exclusion criteria
- < 19 years old
- emergency procedure
- parastomal, lumbar, lateral and subcostal hernia
- multiple staged procedure
- patients undergoing enterocutaneous fistula repair without concomitant abdominal wall defect reconstruction
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL56765.018.16 |