Using electroencephalography to relate behavioural research on Autism Spectrum Disorder (ASD) to electrophysiological findings.
ID
Source
Brief title
Condition
- Communication disorders and disturbances
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome parameter is EEG, but also EOG, ECG, and GSR will be
recorded.
Secondary outcome
Not applicable.
Background summary
Psychiatric diagnoses are based on behavioural characteristics. However, the
focus on neurobiological substrates of this behaviour is increasing, influenced
by the development of new techniques that focus on biological instead of
behavioural derivatives of brain activity.
Study objective
Using electroencephalography to relate behavioural research on Autism Spectrum
Disorder (ASD) to electrophysiological findings.
Study design
We will examine the electrophysiological basis of two phenotypical observations
in ASD: deviant social behaviour and deviant emotion regulation. Based on
previous research, social behaviour will be related to resting-state EEG.
Emotion regulation will be related to the late positive potential (LPP).
Study burden and risks
No risks are anticipated. The electrophysiological measures (EEG, EOG, ECG,
GSR), the behavioural measures (the three used questionnaires), and the used
stimuli during the tasks have been used many times before without any problems.
Dennenhout 1
Barendrecht 2994GC
NL
Dennenhout 1
Barendrecht 2994GC
NL
Listed location countries
Age
Inclusion criteria
Diagnosis of Autism Spectrum Disorder, IQ of 85 or higher based on recent (not older than two years) examination. When IQ is not known based on recent examination, a new test can be administered. This will be done after consulting the potential participant.
Exclusion criteria
Sensory impairments (e.g. blindness), secondary psychiatric disorders that might impact the dependent variables (e.g. social anxiety), no stable medication use (during the last three months).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL57428.101.16 |