The main objective is to investigate the additional value of CRP-POCT (C-reactive protein point-of-care-test) testing in patients suspected of airway infections in long-term care facilities.
ID
Source
Brief title
Condition
- Bacterial infectious disorders
- Respiratory tract infections
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main study parameters/endpoints: The main endpoint is a difference in
first-consult-prescribed antibiotic use in patients who had a CRP test.
Secondary outcome
- relation between height of CRP and number of antibiotic prescriptions
- relation between parameters for illness and number of antibiotic prescriptions
- the value of pre-test illness according to the physician.
Background summary
Rationale: Patients in long-term care facilities often receive treatment for
health-care associated infections based on history and physical examination. We
aim to study the additional value of a CRP test on top of the *best common
practice*.
Nature and extent of the burden and risks associated with participation,
benefit and group relatedness: Both patient groups receive best common
practice. On top of that, the intervention group receives an extra test, which
is a *finger-prick* to catch a small amount of blood, one drop. This test
taking will hurt somewhat, but a regular venous blood taking has more
disadvantages, i.e. chance of a hematoma, requires transportation to a
laboratory. As patients stay inside their living, there is no hospital visit
necessary and there are no questionnaires to fill in. We think this study is
therapeutic, since in other populations (primary care) CRP POCT testing already
is proved to be effective.
Study objective
The main objective is to investigate the additional value of CRP-POCT
(C-reactive protein point-of-care-test) testing in patients suspected of airway
infections in long-term care facilities.
Study design
Location-randomised explorative pilot study.
Intervention
The intervention will consist of one blood test for the patiënt and a
questionnaire for the physician.
Study burden and risks
Both patient groups receive best common practice. On top of that, the
intervention group receives an extra test, which is a *finger-prick* to catch a
small amount of blood, one drop. This test taking will hurt somewhat, but a
regular venous blood taking has more disadvantages, i.e. chance of a hematoma,
requires transportation to a laboratory. As patients stay inside their living
room, there is no hospital visit necessary and there are no questionnaires to
fill in for the subjects. We think this study is therapeutic, since in other
populations (primary care) CRP POCT testing already is proved to be effective.
Barones van Lyndenlaan 1
Bennekom 6721PK
NL
Barones van Lyndenlaan 1
Bennekom 6721PK
NL
Listed location countries
Age
Inclusion criteria
All institutionalized patiënts with suspected airway infection
Exclusion criteria
Patients, or their first legal representative, who do not sign the informed consent, will be excluded. Also, if the physician wants to give antibiotics nonetheless, patients will be excluded and if a patient doesn*t want to receive antibiotic treatment anymore, exclusion will follow as well. If a patiënt, representative or physician assesses the test as too painful or traumatic for the patient.
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL58820.091.16 |