The aim of our study is to measure 1) the prevalence of signs of child abuse and neglect in children with functional defecation disorders, 2) whether signs of child abuse and neglect are more common in children with functional defecation disorders…
ID
Source
Brief title
Condition
- Gastrointestinal motility and defaecation conditions
- Family issues
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary endpoint is the prevalence of evidence for abuse from history, physical
examination or additional investigations in children with functional defecation
disorders compared to the control group.
Secondary outcome
Secondary endpoint is the prevalence of stressful life events and traumatic
symptoms in children with functional defecation disorders compared to the
control group.
Background summary
Constipation en FNFRI are common problems in childhood. The pathophysiology of
functional defecation disorders is probably multi-factorial and is largely
unknown. From previous studies in children is known that maltreated children
were more likely to have defecation disorders than healthy children. From
studies in adults is known that adults suffering from functional
gastrointestinal symptoms were more likely to have a history of child abuse or
sexual abuse than adults suffering from organic gastrointestinal symptoms.
Study objective
The aim of our study is to measure 1) the prevalence of signs of child abuse
and neglect in children with functional defecation disorders, 2) whether signs
of child abuse and neglect are more common in children with functional
defecation disorders than in children with functional abdominal pain and 3)
whether stressful life events and traumatic symptoms are more common in
children with functional defecation disorders than in children with functional
abdominal pain.
Study design
A case-control study will be carried out in which the amount and size of
stressful life events and signs of abuse in children with functional defecation
disorders will be evaluated and compared with children with functional
abdominal pain and healthy children. Patients with functional defecation
disorders and patients with functional abdominal pain will be recruited from
the outpatient clinic of the Emma Children*s Hospital. In these study groups,
interviews and questionnaires will be completed in the outpatient clinic.
Study burden and risks
In theory, the study could be confronting for children who have experienced
unpleasent events. However, we consider an early signaling and treatment of
such a problem as important that we can justify further research. The
investigations are not invasive and will be performed by trained professionals.
Meibergdreef 9
Amsterdam 1105AZ
NL
Meibergdreef 9
Amsterdam 1105AZ
NL
Listed location countries
Age
Inclusion criteria
1) Patients aged 3-10 years old presenting at our specialized outpatient clinic with functional defecation disorders including functional constipation and functional non-retentive fecal incontinence (FNRFI) according to the ROME III criteria.
2) Patients aged 3-10 years old presenting at the outpatient clinic with functional abdominal pain according to the ROME III criteria.
3) School children aged 3-10 years old without gastro-intestinal complaints or chronic ilness
Exclusion criteria
1) General exclusion criteria:
-Parents with too little knowledge of the Dutch language to fill out the questionnaires.
-Parents with a too low intelligence quotient to fill out the questionnaires.
-Children with an intellectual disability who are unable to answer questions during the interview.
2) Index group:
-Children with constipation due to organic causes or surgical operations.
-Children with constipation due to medication.
3) Control group; functional abdominal pain:
-Children with abdominal pain due to organic causes or surgical operations.
-Children with abdominal pain due to medication.
4) Control group; healthy children:
-Children with gastro intestinal complaints (such as abdominal pain or constipation)
-Children with other chronic ilness
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL35893.018.11 |