The primary objective of this study is to investigate the acute effects of a Breinspijs meal on the cognitive domains attention, processing speed, working memory and episodic memory. Secondary objectives are the effects of a Breinspijs meal on…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
optimaal cognitief functioneren
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study parameter is the difference in performance on attention,
processing speed, episodic memory and working memory, measured with a battery
of sensitive cognitive tests.
Secondary outcome
Secondary study parameters are the difference in arousal and the difference in
response of salivary cortisol levels. Additional measures include feelings of
fatigue, hunger, satiety, and mood and general variables that are relevant to
characterize the participants and may be affecting the outcome.
Background summary
The influence of nutrition on cognitive functioning on the short- and long-term
has been acknowledged in many studies. However, little attention has been paid
to the acute effects of nutrition on cognitive functioning, which may be of
interest in working and learning situations. Furthermore, the majority of
studies investigated the effect of single nutrients, which are not
representative of everyday eating behaviour. Only a few studies looked at the
effect of whole meals, which may yield larger, synergistic effects (Mahoney,
Taylor, & Kanarek, 2005). However, most studies that were performed on meals
and cognitive performance are conducted in elderly or children, research in
adults is largely lacking (Adolphsen et al., 2016). In addition to that, the
limited amount of studies that has been performed investigated the effects of
breakfast or lunch. Only one study investigated the effect of an evening meal,
but this was compared to consumption of no evening meal (Smith, Maben, &
Brockman, 1994). We hypothesize that young adult participants will have a
better cognitive functioning on selected cognitive domains after consumption of
an evening meal targeted to optimize cognitive functioning as compared to a
control meal. We will include the additional parameters arousal and salivary
cortisol levels, which may play a role in this relation.
Study objective
The primary objective of this study is to investigate the acute effects of a
Breinspijs meal on the cognitive domains attention, processing speed, working
memory and episodic memory. Secondary objectives are the effects of a
Breinspijs meal on arousal and salivary cortisol levels and to relate these to
the effects on the four cognitive domains.
Study design
Counterbalanced, randomized, cross-over design with two conditions.
Intervention
Breinspijs meal and a control meal.
Study burden and risks
Each participant will attend two test sessions that each last 2 hours. A test
session comprises consumption of a Breinspijs meal or a control meal,
collection of two salivary samples, filling out several short questionnaires
and performing cognitive tests. The meals consist of regular meal ingredients
and have a regular portion size. The risks and burden involved in participating
in this study are minimal.
Stippeneng 4
Wageningen 6708 WE
NL
Stippeneng 4
Wageningen 6708 WE
NL
Listed location countries
Age
Inclusion criteria
- Male
- Aged 18-40 years
- Dutch nationality
Exclusion criteria
- Regular smoker: someone who currently smokes one or more manufactured or hand rolled tobacco cigarettes, cigars or tobacco-pipes per day.
- Diagnosis of adrenal gland disorder: Addison Disease, Cushing's Syndrome, congenital adrenal hyperplasia, primary hyperaldosteronism, pheochromocytoma, adrenal gland carcinoma.
- Diagnosis of a sleep disorder: insomnia, parasomnia, hypersomnia, sleep-related breathing disorder, circadian rhythm sleep disorder, sleep-related movement disorders (Hirotsu, Tufik, & Andersen, 2015).
- Diagnosis of a psychiatric disorder.
- Oral health problems: diseases, inflammation, lesions.
- Allergic, intolerant or hypersensitive to lactose, egg, nuts, wheat, fish, and/or gluten.
- Unwilling to consume meat, fish, dairy products and/or any of the other ingredients in the BreinspijsTM or control meal.
- Reported slimming in the last 2 months.
- Use of drugs in the week before participation and during the study.
- Extensive small or big appetite.
- Employees at the Division of Human Nutrition of Wageningen University & Research.
- Performing a thesis or internship at the Division of Human Nutrition of Wageningen University & Research.
- Current participation in other scientific research with the exception of EetMeetWeet!.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL62653.081.17 |