The objective of this study is to explore the effects of spinal anesthesia on hemodynamic parameters of fluid status, especially vena cava inferior diameter and collapsibility. TFurthermore, the correlation between vena cava inferior collapsibility…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
effecten van anesthesiologische handelingen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
effect of spinal anesthesia on vena cava inferior collapsibility, and
interrater variability of transthoracic ultrasound assessment of vena cava
inferior diameter and collapsibility
Secondary outcome
correlation between vena cava inferior collapsibility and peroperative
hypotension
Background summary
Spinal anesthesia is a safe, frequently used anesthetic technique. The main
side effect of spinal anesthesia is hypotension, occuring in up to 85 % of
selected cases. This hypotension is often treated with fluid infusion. However,
especially in elderly patients, high volume fluid infusion can lead to fluid
overload.
The effects of spinal anesthesia on preload and fluid responsibility are not
exactly known. Hence, therapy for hypotension after spinal anesthesia might not
be adequate. With transthoracic echocardiography, vena cava inferior diameter
and collapsibility can be used to monitor fluid responsiveness and guide fluid
management.
Study objective
The objective of this study is to explore the effects of spinal anesthesia on
hemodynamic parameters of fluid status, especially vena cava inferior diameter
and collapsibility. T
Furthermore, the correlation between vena cava inferior collapsibility and the
occurence and degree of hypotension after spinal anesthesia will be explroed.
Study design
Observational pilot study
Study burden and risks
The burden of this study will be the performance of multiple transthoracic
echocardiography exams. No medication will be given and no other intervention
will take place. No changes in anaesthetic practice will occur upon entering
the study.
Michelangelolaan 2
Eindhoven 5623 EJ
NL
Michelangelolaan 2
Eindhoven 5623 EJ
NL
Listed location countries
Age
Inclusion criteria
- Adult age (>18 years)
- Written informed consent
- Minor surgery under the umbilicus, e.g. herniorapphy, transurethral resection of bladder or prostate, orthopaedic procedures
- ASA class I or II
Exclusion criteria
- No informed consent
- ASA class III or higher
- Obstetric surgery
- Emergency procedures
- Pre-existing neurological injury or disease
- Contra-indications for spinal anesthesia (e.g. coagulation abnormalities)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| ClinicalTrials.gov | NCT02315937 |
| CCMO | NL50108.060.14 |