• Characterization of methylation patterns in blood samples and finding of methylation patterns that are unique to lung cancer.• Development of a molecular test for early diagnosis of lung cancer from a blood sample that will be more sensitive and…
ID
Source
Brief title
Condition
- Respiratory and mediastinal neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Methylation patterns that are unique to lung cancer.
Secondary outcome
None
Background summary
The aim of this study is to find methylation patterns that are unique to lung
cancer and to develop a blood test for early diagnosis of lung cancer based on
methylation biomarkers.
Study objective
• Characterization of methylation patterns in blood samples and finding of
methylation patterns that are unique to lung cancer.
• Development of a molecular test for early diagnosis of lung cancer from a
blood sample that will be more sensitive and specific than existing tests.
Study design
Single blood draw of 30 ml in 1000 subjects from the test group and 1000
subjects from the control group.
Intervention
Single blood draw of 30 ml.
Study burden and risks
Single blood draw of 30 ml.
Pekeris Street 3
Rehovot 7670203
IL
Pekeris Street 3
Rehovot 7670203
IL
Listed location countries
Age
Inclusion criteria
Males and females
Test group: subjects18 years and above with a suspicion of a cancerous tumor in the lungs or patients who have already been diagnosed with lung cancer, however did not yet undergo surgery and did not yet receive any treatment for the cancer (including, but not limited to chemotherapy and/or radiation).
Control group: Smokers (currently or in the past) 50 years and above without cancer (current or previous) with preference to subjects which also diagnosed with COPD.
Exclusion criteria
Test group: Subjects with cancer or history of cancer from any kind (besides lung cancer).
Control group: Subjects with cancer or history of cancer from any kind.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL61024.100.17 |