Main objective: Collecting and setting up norm values for the SRT-Wpeak for healthy young adults between 19 and 24 years. Secondary objectives: [1] Determine the reproducibility of the SRT; [2] Determine the relationship between the SRT-Wpeak and…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
cardiorespiratoire fitheid
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
SRT-Wpeak
CPET-VO2peak
Secondary outcome
Demography (age, sex); Anthropometry (height, weight, lungfunction, % bodyfat);
Background summary
Despite its clinical relevance, the use of formal cardiopulmonary exercise
testing (CPET) seems to be underused in current usual clinical practice.
Currently, the Steep Ramp Test (SRT) has proven to be a reliable and valid
alternative, without the need for use of respiratory gas analysis measurements.
However, norm values for (young) adults are lacking and regression equations to
predict peak oxygen uptake (VOpeak) out of the peak workload attained during
the SRT (SRT-Wpeak) are developed in specific patients, which hampers its
feasibility.
Study objective
Main objective: Collecting and setting up norm values for the SRT-Wpeak for
healthy young adults between 19 and 24 years. Secondary objectives: [1]
Determine the reproducibility of the SRT; [2] Determine the relationship
between the SRT-Wpeak and different anthropometric parameters; [3] Determine
the relationship (criterion validity) between the CPET-VO2peak and the
SRT-Wpeak and different anthropometric parameters.
Study design
Observational (cross-sectional) study. Seventy healthy, young adult
participants in the age between 19 and 24 years will undergo a screening
procedure and perform a SRT in the Exercise laboratory of the University of
Applied Sciences Utrecht. Within two weeks afterward, participants will perform
a CPET (n=24) or a second SRT (n=46) based on randomization. All tests and
procedures will be performed in the Exercise Laboratory of the University of
Applied Sciences, Institute of Movement Studies, Utrecht.
Study burden and risks
The risks associated with study participation are negligible as the SRT is
already part of usual care in higher risk patient categories as heart failure,
COPD, status after chemotherapy and diabetes. Furthermore, risks associated
with CPET are negligible in proper screened, young, sports participating
healthy adult participants without any clinical complaints who, probably,
already take part in high-intensity sports activities. The facilities of the
exercise laboratory entirely fullfills the safety criteria for exercise testing
in this particular population.
Heidelberglaan 7
Utrecht 3584 CS
NL
Heidelberglaan 7
Utrecht 3584 CS
NL
Listed location countries
Age
Inclusion criteria
Healthy young adults between 19 and 24 years.
Exclusion criteria
* A medical status that contraindicates exercise testing (using the ACSM Risk Stratification Questionnaire)
* The use of medication affecting exercise capacity (e.g. beta block)
* Smoking
* Comorbidity that affects exercise response and exercise capacity
* Impaired motor development;
* Morbid obesity (BMI>35kg/m2);
* Insufficient understanding of the Dutch language
* Not meeting Dutch Healthy Exercise Norms (Nederlandse Norm Gezond Bewegen)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL59559.041.16 |