We aim to study the link between behavioural and psychological determinants and chlamydia (re-)infection, and to develop mathematical models for curable STI incorporating these determinants to be able to better estimate the impact of interventions.
ID
Source
Brief title
Condition
- Chlamydial infectious disorders
- Ovarian and fallopian tube disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main parameters of the study are chlamydia (re-)infection and demographic,
behavioural and psychological determinants.
Secondary outcome
N/A
Background summary
Chlamydia is the most commonly reported STI in the Netherlands and the number
of reported cases has been increasing in the past few years. Control of this
infection is of public health importance, because chlamydia infections are
associated with increased risk of serious reproductive consequences, such as
pelvic inflammatory disease (PID), ectopic pregnancy and infertility. However,
control of chlamydia has proven to be challenging; reasons for this might be
high re-infection rates after treatment. Therefore, behaviour change after a
diagnosis might be vital to reduce re-infection rates. In addition, because
most people are unaware of their infection, preventive health actions (such as
using condoms) depend on psychological determinants, making the incorporation
of such determinants in models especially important in this field. Ultimately,
the data collected in the clinical study will be used to parameterise a
mathematical model, which will provide valuable information for public health
policy makers to guide which intervention measures should be prioritised and
conducted in the future.
Study objective
We aim to study the link between behavioural and psychological determinants and
chlamydia (re-)infection, and to develop mathematical models for curable STI
incorporating these determinants to be able to better estimate the impact of
interventions.
Study design
The aim of the clinical study (longitudinal cohort study) is to collect data on
sexual behaviour and psychological determinants from people visiting STI
clinics. Participants are enrolled for a year, and questionnaires are
administrated at four time points: at baseline, 3 weeks, 6 months and at one
year follow-up. To be able to link behavioural and psychological determinants
to (re-)infections, participants will be tested for chlamydia at enrolment and
at 6 months follow-up.
Study burden and risks
There are no health risks associated with participation. However, participants
may experience some discomfort by the personal nature of the questionnaire and
by the collection of vaginal swabs and urine samples (at the STI clinic and at
home).
Antonie van Leeuwenhoeklaan 9
Bilthoven 3721 MA
NL
Antonie van Leeuwenhoeklaan 9
Bilthoven 3721 MA
NL
Listed location countries
Age
Inclusion criteria
- Being a heterosexual man or woman
- Between 18 and 24 years old;
- Not notified by partner
Exclusion criteria
- Not living in the Netherlands
- Inability to read or speak Dutch
- Men who have sex with men (MSM), women who have sex with women (WSW) and men/women who have sex with both men and women
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL57481.094.16 |
| OMON | NL-OMON28873 |