The main objective of this study is to assess the one-year survival and quality of life of patients after CPR for in-hospital cardiac arrest. The secondary objectives are to assess if there are patient-related predicting factors for these outcome…
ID
Source
Brief title
Condition
- Heart failures
- Fatal outcomes
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study endpoints are one-year survival and quality of life.
Secondary outcome
Secondary endpoints are direct survival and survival to discharge.
Background summary
In-hospital cardiac arrest (IHCA) is a serious adverse event for which
cardiopulmonary resuscitation (CPR) can be performed to restore circulation.
Currently survival after IHCA is poor. To assess the success of resuscitation
attempts there is a need for research that focuses on long-term survival and
quality of life. Patient selection for CPR and improvement of CPR techniques
are crucial for improving qualitative survival.
Study objective
The main objective of this study is to assess the one-year survival and quality
of life of patients after CPR for in-hospital cardiac arrest. The secondary
objectives are to assess if there are patient-related predicting factors for
these outcome measures and to assess whether outcomes are influenced by
hospital-related factors (CPR quality and treatment options.)
Study design
The current study has a prospective, observational design, with a 12-month
follow-up. Patients will be included from January 1st 2017. Patient data
collection will take place at four time points: T0= directly post-CPR, T1= at
hospital discharge or at in-hospital death, T2= 3 months after CPR, T3= 12
months after CPR. Clinical data will be collected at all time points. Quality
of life data will be collected at T2 and T3 by means of validated
questionnaires. General hospital data and data concerning the level of
CPR-training will be ascertained at four moments during the first year of
patient inclusion.
Study burden and risks
The burden of participation consists of filling out a questionnaire at 3 months
and 12 months after CPR. The questionnaire focuses on physical and
psychological wellbeing, as well as the burden of disease and (new) comorbid
conditions. Considering the vulnerability of the study population and the
nature of the questions, patients will be provided with a contact address for
further psychological help. The risk for adverse events is considered to be
negligible.
's Gravendijkwal 230
Rotterdam 3015CE
NL
's Gravendijkwal 230
Rotterdam 3015CE
NL
Listed location countries
Age
Inclusion criteria
A patient:
- receiving cardiopulmonary resusciation for a circulatory arrest. CPR is defined as chest compressions.
- aged 18 years or older.
- in whom circulatory arrest occurs in-hospital. This includes: wards/outpatient clinics/ hallways/operating rooms/cardiac care units/intensive care units/emergency rooms.
Exclusion criteria
A patient:
- who is a child (<18 years of age).
- in whom circulatory arrest is purposely induced; e.g. in cardiac surgery.
- in whom an arrhythmia is purposely induced; e.g. in electrophysiological treatment.
- who refuses to participate.
- who has suffered primary out-of-hospital cardiac arrest with re-arrest <24h after hospital admission.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL55661.078.16 |
| OMON | NL-OMON23932 |