Providing a better understanding of auditory percepts produced by an Auditory Brainstem.
ID
Source
Brief title
Condition
- Hearing disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Matching pitch and loudness perception to get a better understanding of what a
patient hears with his/her ABI, in comparison to the contralateral ear.
Secondary outcome
To explore the perceptual characteristics of single electrode stimulation via
an ABI.
To determine the binaural advantages concerning sound localization and speech
discrimination in patients with an ABI and contralateral normal hearing.
Background summary
An auditory brainstem implant (ABI) is a type of hearing device, often used for
patients with neurofibromatosis type 2. It differs from the cochlear implant in
the sense that the electrodes are not placed inside the cochlea but on the
cochlear nucleus in the brainstem. This also results in poorer speech
understanding with the ABI. An ABI is primarily used in patients in whom the
cochlear nerve is damaged, or when placement of an electrode array in the
cochlea is not possible. Thus far, patients with neurofibromatosis type 2 are
only eligible for an ABI when they suffer from severe bilateral hearing loss.
Because of this, it remains unclear what a patient hears with his/her ABI. An
on-going study by van den Berge et al. performed at the UMCG evaluates the
effect of ABI implantation on tinnitus in patients with unilateral hearing loss
and ipsilateral tinnitus. This group of patients gives us a unique opportunity
to examine the auditory percepts produced by an ABI via psychoacoustic tests in
which the participant compares electric stimuli presented by the ABI to
acoustic stimuli.
Study objective
Providing a better understanding of auditory percepts produced by an Auditory
Brainstem.
Study design
This is a single-centre, observational study with a maximum of 10 patients
derived from the ongoing ABI study (ABR nr. NL55276). There will be no control
group.
Study burden and risks
Patients will have to visit the UMCG for a total of 2 times to perform 5
different audiological experiments. These experiments will pose no risk to the
health of the patient. Participating in this research could provide a better
insight in the psychoacoustics of the ABI and the function of the cochlear
nucleus. This in turn can help future assessment of possible suitable
candidates for the ABI. Furthermore, more knowledge of the cochlear nucleus is
required to optimally adjust the ABI, so that patients can have the most
optimal hearing experience.
Hanzeplein 1
Groningen 9700 RB
NL
Hanzeplein 1
Groningen 9700 RB
NL
Listed location countries
Age
Inclusion criteria
Patients with assymmetrical hearing loss and an ipsilateral auditory brainstem implant
Exclusion criteria
Symmetrical hearing loss, unilateral deafness, no audiotory brainstem implant
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL68854.042.19 |