To compare the bias, limits of agreement and precision of the TOF cuff relative to EMG during recovery of moderate and deep neuromuscular block in patients with normal body mass index and morbidly obese patients. All techniques are currently used at…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
anesthesie
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The outcome of the monitor devies
Secondary outcome
None
Background summary
Neuromuscular monitoring is mandatory during anesthesia. Acceleromyography
(AMG) is the most wide spread used method because it is easy to apply and
accurate enough for daily practice. However AMG is known to be inaccurate when
compared to the gold standard in neuromuscular transmission monitoring,
electromyography (EMG). Furthermore when the patient*s arms require to be
positioned next to the body and beneath surgical drapes, AMG measurements are
often hindered and inaccurate. The TOF cuff is a device, which measures NMB at
the upper arm with a blood pressure cuff. It overcomes the previously mentioned
disadvantages of AMG. However, it validity compared to EMG has not yet fully
been investigated.
Study objective
To compare the bias, limits of agreement and precision of the TOF cuff relative
to EMG during recovery of moderate and deep neuromuscular block in patients
with normal body mass index and morbidly obese patients. All techniques are
currently used at LUMC and all devices have CE marking for the intended use.
Study design
Observational, open design
Study burden and risks
None
Albinusdreef 2
Leiden 2333 ZA
NL
Albinusdreef 2
Leiden 2333 ZA
NL
Listed location countries
Age
Inclusion criteria
(i) ASA class I-III
(ii) > 18 years of age;
(iii) Ability to give oral and written informed consent.
Exclusion criteria
(i) Known or suspected neuromuscular disorders impairing neuromuscular function;
(ii) Allergies to muscle relaxants, anesthetics or narcotics;
(iii) A (family) history of malignant hyperthermia;
(iv) Women who are or may be pregnant or are currently breast feeding;
(v) Renal insufficiency, as defined by a glomerular filtration rate < 30 ml/min
(vi) Scheduled for anesthesia without the use of muscle relaxants.
Design
Recruitment
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
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Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL60865.058.17 |