The aim of this study is to obtain further knowledge on aerosol droplet formation and spread during oxygen therapy.
ID
Source
Brief title
Condition
- Respiratory tract infections
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Aerosol droplet formation (quantification per surface area) and travel
velocity.
Secondary outcome
NA
Background summary
Currently, there is an ongoing global health crisis caused by pandemic
SARS-CoV-2. Health professionals have an increased risk of infection with
SARS-CoV-2 as a result from close contact with patients with COVID-19.
Increased risk of transmission occurs through aerosol droplet formation and
spread during coughing, sneezing but also during aerosol-forming medical
treatments such as suction and intubation of the airways.
At the moment, the precise risks of aerosol droplet formation and spread during
several oxygen therapy modalities, in particular high flow nasal cannula
(HFNC), is unclear. This results in health care professionals to avoid
potentially beneficial oxygen therapy modalities, or cause disproportionate
(too low or too high) risk assessment with regard to personal protection
equipment and procedures.
More knowledge on aerosol droplet formation and spread during different oxygen
therapy modalities is urgently needed.
Study objective
The aim of this study is to obtain further knowledge on aerosol droplet
formation and spread during oxygen therapy.
Study design
Prospective.
In dit onderzoek worden gezonde proefpersonen kortdurend behandeld met zuurstof
via een masker en neusbril. Tijdens deze toediening wordt gevraagd met open en
gesloten mond te ademen en te hoesten. De totale duur voor elk proefpersoon
wordt geschat op 5 minuten.
Tijdens de zuurstoftoediening wordt middels een frame met laser licht aerosol
druppel vorming gedetecteerd met video software analyse achteraf.
In this study, healthy volunteers will be treated for a short period with
oxygen via a mask and nasal cannula. During this treatment they will be asked
to breath with open and closed mouth and to cough. The total duration for every
person is estimated at 5 minutes.
During the oxygen treatment aerosol droplet formation will be detected with a
frame with laser beam with video software analysis afterwards.
Study burden and risks
Risk for the participants is negligible. Burden is mild for a short period (5
minutes).
The participants are not related to the study and do not benefit from
participating.
Meibergdreef 9
Amsterdam 1105 AZ
NL
Meibergdreef 9
Amsterdam 1105 AZ
NL
Listed location countries
Age
Inclusion criteria
Healthy volunteers
Exclusion criteria
Chronic respiratory diseases, fever or upper respiratory disease symptoms in
the last 2 weeks prior to participation
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL73585.018.20 |