Explore if it's possible to distinguish conditions (psychopathy, addicition) using experimental computertasks on attention, social cognition and inhibition.
ID
Source
Brief title
Condition
- Personality disorders and disturbances in behaviour
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Examined is wether psychopathic patients (PCL-R totalscore >25) and addicted
patients PCL-R-score * 25 & primary DSM-classification of a Substance Use
Disorder) can be distinguished, based on a cognitive profile of their
individual performance (measured in reaction time and accuracy) on five
experimental tasks.
Secondary outcome
Examined is wether in patients, which are classified as having a 'double
diagnosis' (i.e. being diagnosed with both psychopathy (PCL-R totalscore >25)
and a substance use disorder (DSM-classification), there primary diagnoses can
be distinguished based on their cognitive profile. In the regression model,
age, intelligence, medication, personality and performance on the
neuropsychological screening are added as covariables in order to clarify the
unique predictive validity of the experimental tasks.
Background summary
Antisocial behaviour, substance abuse and their interaction are barriers in
forensic treatment. Especially when a patient has dual diagnosis (addiction &
personality disorder), predicted treatment outcome is poor (MDR
PersoonlijkheidsstoornissenTrimbos, 2008). If this dual diagnosis leads to
criminal transgressions it's a heavy burden for society. The addiction within
this dual diagnosis increases and intensifies criminality, compared to the
personality disorderd group without comorbid addiction (Achtergrondrapport bij
de Richtlijn problematisch middelengebruik in de forensische klinische zorg,
Victas/IVO, 2015). Because of the shortcomings in distinguishing both disorders
with current common psychodiagnostic instruments, choices in treatment focus
are not easily made (Koeter & Maastricht, 2006).
Therefore, in this study we try to clarify the distinction on a
neuropsychological level. The relevance of the usage of neuropsychologic tests
is found in previously demonstrated cognitive problems in two main predictors
of antisocial behaviour: addiction and psychopathy. Both condtions are known
for their distinctive cognitive problems (Field, Munafò, & Franken, 2009;
Newman & Baskin-Sommers, 2011). Because of this double dissociation
experimental tasks will be used on several cognitive domains (i.e. attention,
social cognition and inhibition) in order to discriminate between disorders in
case of dual diagnosis.
Study objective
Explore if it's possible to distinguish conditions (psychopathy, addicition)
using experimental computertasks on attention, social cognition and inhibition.
Study design
An experimental, multi-centre study with mixed design (cross-sectional, between
subject, field experiment) will be performed. Both (incarcerated or outpatient
treated) patients and healthy controls (community sample) will be included.
Study burden and risks
There's no risk in participating in the study: tasks are relatively easy, do
not affect daily functioning and will be conducted by trained researchers in
familiair surroundings. Partcipants will be compensated upon partaking. The
only burden is the time needed for the total test, which will be approximately
2,5 hours. Healthy controls will be invited to the Erasmus Behavioral Lab for
testing; patients will be tested within their own facility in a designated
(test)room.
Emmastraat 75
Arnhem 6828HD
NL
Emmastraat 75
Arnhem 6828HD
NL
Listed location countries
Age
Inclusion criteria
All (wo)men aged 18-65 incarcerated in or in treatment at the partcipating
(forensic) psychiatric facilities, who have signed an informed consent form,
including:
- personality disordered patients;
- addicted patients;
- patients with all other psychiatric disorders, besides psychotic disorders;
- delinquents with known disorder;
- delinquents without (knwon) disorder;
- healthy people recruited from general population, who don't meet exclusion
criteria;
Exclusion criteria
- Schizofrenic / active psychotic patients or bipolar disorderd patients with
psychotic features
- adminstered use of anti-psychotic medication;
- colorblindness of other visual impairment
- IQ < 75
- age <18 or > 65, - controlgroep:
* AUDIT-score >20 (indicatief voor alcoholafhankelijkheid)
* DUDIT-score >25 (indicatief voor drugsafhankelijkheid)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL61928.078.17 |