Primairy objective:Explore the prevalence of the ABI-effect, by mapping the participation level. Secundary objective:Substatiate the occurence of the ABI-effect, by mapping cognitive functions of patients and compare these to healthy controls.…
ID
Source
Brief title
Condition
- Other condition
- Structural brain disorders
Synonym
Health condition
niet-aangeboren hersenletsel (traumatisch hersenletsel, CVA en SAB)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Cohort study:
The percentage of patients experiencing the ABI-effect. Also, a 95% confidence
interval of this prevalence will be calculated.
Case-control study:
The significant difference in cognitive functions between the patient groep and
the healthy controls.
Secondary outcome
Cohort study:
- The degree of decline in participation
- The different areas in which decline in participation is experienced.
- Scores on questionnaires
- Need of care for patients
Case-control study:
- Comparison of scores in two points in time (first and second NPA)
- Performance on neuropsychological tests in different cognitive domains
Background summary
In the Netherlands an estimated 650.000 people live with the daily consequences
of an Acquired Brain Injury (ABI). A substantial amount of these patients
acquired their brain injury (traumatic brain injury, subarachnoïd hemmorhage or
cebrovascular accident) at a relatively young age: between 18 and 50 years old.
The chain-of-care for ABI aims for recovery in the subacute phase, usually
within a period of one year after injury. After an adaptation period, the
patients reach a new balance, with stabilization of complaints and
reintegration, sometimes with the necessity of modifications. The group of
patients who acquired a brain injury at a young age, have to face the effects
of aging like decreased cognitive functions, which can cause the participation
level to drop. This is called the ABI-effect in the current study. At this
moment, insufficient information is available about the functioning of people
who suffered ABI multiple years ago and have established a new balance, and now
make the transition to an older phase of live.
Study objective
Primairy objective:
Explore the prevalence of the ABI-effect, by mapping the participation level.
Secundary objective:
Substatiate the occurence of the ABI-effect, by mapping cognitive functions of
patients and compare these to healthy controls.
Tertiary objective:
Gain insight in the need of care for patients, to enhance regular care after
ABI.
Study design
A prospective cohort study (questionnaires), with an embedded case control
study (neuropsychological assessments) in which the data is gathered whitin a
timeframe of 3 years.
Study burden and risks
The risks for measurements (neuropsychological tests and questionnaires) used
in this study are negligible.
Hanzeplein 1
Groningen 9713GZ
NL
Hanzeplein 1
Groningen 9713GZ
NL
Listed location countries
Age
Inclusion criteria
- acute acquired brain injury (ABI) (traumatic brain injury, subarachnoidal
hemorrhage, cerebrovascular accident
- ABI more than 5 years ago
- ABI at the age of 25 years or older
- current age between 50- 67 years
- able to complete questionnaires independently
- for case-control study: results of an earlier neuropsychological assessment,
that has been done in the non-acute but confined phase after ABI; between 3 and
12 months after injury must be availabe.
Exclusion criteria
- second ABI for which patient was admitted
- psychiatric disease for which the patient is treated
- alcohol and drug abuse
- language barriers or illiteracy limiting filling out questionnaires
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL79072.042.21 |