To demonstrate that cone density can be reliably and accurately measured after vitrectomy for RRD split fovea and for RRD macula-off.
ID
Source
Brief title
Condition
- Retina, choroid and vitreous haemorrhages and vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Cone density.
Secondary outcome
- Intercone spacing,
- Hexagonality,
- Presence of preoperative cystoid macula edema,
- Presence of preoperative proliferative vitreoretinopathy,
- Preoperative and postoperative best-corrected visual acuity of operated eye,
- Time between onset symptoms and time of surgery (in days),
- Integrity of ellipsoid zone and external limiting membrane within 500 µm
around the foveal center,
- Foveal detachment height,
- Usage of perfluorcarbon liquid.
Background summary
Although OCT provides a detailed visualization of the retina in vivo, some
complaints after vitrectomy for rhegmatogenous retinal detachment (RRD) remain
unexplained. Adaptive optics flood illumination ophthalmoscopy (AO-FIO), an
imaging technique visualizing individual cones, may provide more insight into
damage and recovery of photoreceptor cells after RRD.
Study objective
To demonstrate that cone density can be reliably and accurately measured after
vitrectomy for RRD split fovea and for RRD macula-off.
Study design
Prospective, observational pilot.
Study burden and risks
Participation involves neither additional risk nor benefit. Extra study-related
time is 3 hours in total.
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Listed location countries
Age
Inclusion criteria
- Vitrectomy for RRD macula-off or for split fovea
Exclusion criteria
- Age < 18 years,
- No ability to attend follow-up visits,
- No ability to give informed consent.
Eye-related exclusion criteria for both eyes (post-RRD eye and fellow eye):
- Pupil size < 4 mm,
- Pre-existing maculopathy,
- Opacities in the cornea or lens,
- Irregular cornea,
- Instable tearfilm,
- Macular pucker stage 2 or more,
- Cystoid macular edema,
- Subretinal fluid,
- Macular fold,
- Myopia > 12 diopters,
- Hypermetropia > 6 diopters,
- Peroperative peeling of the inner limiting membrane,
- Silicone oil as a tamponade.
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL85899.078.24 |