Amino acids in the blood after intake of high-protein dairy products

1. Age ≥ 18 and ≤ 40 years at the time of ICF signature
2. Body Mass Index (BMI) ≥ 18.5 and ≤ 29.9 kg/m2
3. Signed informed consent
4. Willingness and ability to comply with the protocol
5. Judged by the Investigator to be in good health 

1. Any known surgery or ongoing medical condition that interferes significantly with protein 
absorption and digestion, and/or gastrointestinal (GI) function (e.g. phenylketonuria, 
pancreatitis, short bowel syndrome, inflammatory bowel disease, gastroesophageal reflux 
disease, celiac disease, gastric ulcer, chronic gastritis, gastrointestinal cancer, oesophageal 
and/or gastric surgery), in the opinion of the investigator. 
2. Known renal or hepatic diseases that may interfere with protein metabolism, including 
but not limited to acute hepatitis, chronic liver disease, nephritis, cystinuria, chronic 
kidney disease, in the opinion of the investigator.
3. Use of systemic medication within the past 3 weeks prior to screening which in the 
opinion of the investigator may influence gastric acid production and/or gastrointestinal 
motility or function and/or protein metabolism (for example: antibiotics, anticonvulsants, 
prokinetics, antacids or gastric acid inhibitors, opioid analgesics, anticoagulants, 
corticosteroids, laxatives, growth hormone, testosterone, immunosuppressants, or 
insulin). 
4. Known Diabetes Mellitus type I or type II, insulin resistance, or metabolic syndrome.
5. Any ongoing cancer and/or cancer treatment (except for non-melanoma skin cancer or 
carcinoma in situ).
6. Known anaemia. 
7. A blood donation within 56 days (8 weeks) for men; or 122 days (4 months) for women; 
prior to the screening.
8. Any known bleeding disorder.
9. Adherence to a strict dietary regime (e.g. vegetarian/ vegan/ paleo/ketogenic/ 
intermittent fasting/ high protein diet (>1.6 g/kg body weight/day) or a weight loss 
program.
10. Any known allergies or intolerances to ingredients of the study product, i.e. cow’s milk 
allergies, lactose intolerance.
11. Known pregnancy and/or lactation.
12. Current smoking / vaping/ use of e-cigarette or stopped smoking for < 1 month prior to 
screening (except for incidental smoking of ≤ 3 cigarettes/ e-cigarettes/cigars/pipes per 
week on average in the last month prior to screening).
13. Average alcohol use of > 21 glasses per week for men or > 14 glasses per week for 
women (on average during the last 6 months prior to screening). 
14. Drug or medicine abuse in opinion of the investigator. 
15. Current eating disorder, e.g. anorexia nervosa, bulimia nervosa, binge eating disorder.
16. Use of protein, amino acid, or creatine supplements within 4 weeks prior to screening.
17. Known difficulties with placement of and/or blood drawings from a cannula. 
18. Participation in any other clinical study with investigational or marketed products 
concomitantly or within four weeks before study visit 1. 
19. Major medical or surgical event requiring hospitalization within the preceding 3 months 
and/or scheduled in the period of study participation relevant in the opinion of the 
investigator.  
20. Investigator’s uncertainty about the willingness or ability of the participant to comply 
with the protocol requirements.
21. Employees of Danone Research and of the investigational site and/or their family 
members or relatives.