13521 results
To support the AstraZeneca ARTEMIDE-Gastric01 clinical trial by testing for PD-L1 and HER2 expression in FFPE tumor specimens for eligibility and stratification.The primary objective of this clinical performance study is to evaluate the…
To test the hypothesis that paclitaxel-coated balloon treatment of vulnerable lipid-rich plaques leads to a greater reduction of the lipid-core burden index than guideline-directed medical therapy alone.
The main aim of the current study is to adequately assess HRQoL in patients with stage III TNBC receiving current standard (neo)adjuvant systemic therapy. These outcomes can then be used as a HRQoL benchmark for patients with stage III TNBC treated…
The primary objective of the study is to explain poor speech understanding at an individual level, with the ultimate goal of finding optimal personalized settings for the speech processor. We use the new measurement method of direct stimulation…
The main objective of this study is to develop a diagnostic model with high sensitivity and specificity to help pediatricians to recognize malignancy and minimalize unnecessary referral in children with lymphadenopathy. Moreover, we will perform a…
Better knowledge of the clinical phenotype/natural history and genotype of Traboulsi Syndrome.
In this study, we investigate the possibility of preoperatively estimating the risk of complications in patients using the FitMáx, VSAQ, and PREOP checklist. These questionnaires are automatically administered via the Mijn MMC patient portal two…
Primary Objective: To develop and validate a knowledge questionnaire as an improved version of our RAK-Q 1.0 (phase 1 and 2). Afterwards we will create a CAT (phase 3).
Primary: Can the AI pain assistant accurately inquire about postoperative pain (NRS) and all its dimensions, including location, type of pain, and any aggravation with movement? Secondary: review by a healthcare professional (quality and…
Feasibility of exergaming to reduce sedentary time in persons with an LVAD: The Heart-eXg LVAD-study
To determine the feasibility of tailored exergaming for persons with a LVAD (acceptability, the demand, the implementation, practicality, adaption, expansion, and perform limited-efficacy testing).
The primary objective of this study is to compare the effectiveness of two app-based interventions on diet quality and perceived stress compared to standard care.
This study has been transitioned to CTIS with ID 2023-509142-35-00 check the CTIS register for the current data. Primary objective: To assess the effects of non-vitamin K oral anticoagulants (NOACs) versus no anticoagulation on the co-primary…
The primary objective of this trial is as follows:• To determine the pharmacokinetics of micafungin 300 mg given twice weekly on Mondays and Thursdays in patients at risk for developing an invasive fungal disease (patients who are being treated for…
PSY-PGx is the first initiative to propose a large-scale non-industry sponsored clinical study that aims to demonstrate the clinical benefits and potential of the implementation of pharmacogenetics for psychiatric patients in existing medical…
The ultimate aim of this project is to answer the question whether insufficient EN should or should not be supplemented with PN early in the disease course of critical illness in children. Current medical practice and expert panels advocate the…
This study has been transitioned to CTIS with ID 2024-517115-70-00 check the CTIS register for the current data. Primary Objective: The goal of the study is to evaluate hemostasis, such as coagulation activation/thrombin generation and platelet…
The objective is to assess the effectiveness of exercise therapy (running therapy or Nordic walking) ondepression in adults, in addition to usual care (primary aim) and on metabolic syndrome measures, qualityof life and cost effectiveness (secondary…
The primary objective is to assess whether dual mobility cups reduce the risk of dislocations in patients with a femoral neck fracture treated with a THA by 50% within one year, as suggested by observational data.
This pilot study aims to assess the feasibility of procedures for a future randomised multicentre trial (RCT) on IMT effectiveness after weaning from MV and to gather patient and physiotherapist experiences with IMT.
For Lilly's study (drug study)Primary Objectives:Dose Optimization- To determine the optimal dose of LY3537982 (50 or 100 mg BID) to be administered in combination with pembrolizumabSafety Lead-In- To determine the dose of LY3537982 to be…