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A study to evaluate the bioequivalence of Orfadin capsules 20 mg compared to Orfadin capsules 10 mg. An open-label, randomized, cross-over, single-dose study in healthy volunteers.

The primary purpose of the study is to investigate whether the new 20 mg capsule of Orfadin® (nitisinone) has a similar bioavailability in the body (gives the same concentration in the blood) as two of the marketed capsules of 10 mg. The secundary…

Aspects of bracing in adolescent idiopathic scoliosis

Objective: The primary objective of the study is determining the contributing factors in  bracing for AIS. The contributing factors are determined as factors of influence in the  corrective possibilities and therefore end term…

Treatment Effect of Bone Anchored Protraction in Cleft Patients

Bone-anchored maxillary protraction therapy improves facial profile in cleft children.