17 results
The aim of this study is to identify barriers and facilitators for successful implementation of the care pathway, to ultimately inform national scale-up of the pathway.
We hypothesize that sleep apnea screening, using a combination of an online questionnaire and high resolution overnight oximetry, can safely be applied to exclude sleep apnea with high sensitivity (≥97%) and acceptable specificity (≥60%) in patients…
Primary objectives: - To examine how environmental exposures influence the prevalence, 5-year incidence and progression of cardiometabolic and chronic respiratory disease in the general population. - To determine the mediation effect of lifestyle…
Development of new imaging techniques for MR-guided motion management in the presence of respiratory motion
To evaluate the safety, feasibility and efficacy of an 8-week remotely supervised home-based maintenance exercise training program following pulmonary rehabilitation in patients with COPD.
The aim of this project is to evaluate the clinical value of biomarkers in adult patients with pulmonary hypertension, in particular:1) To quantify biomarkers of neurohormonal activity as NTproBNP, endotheline-1 and of immunological activity as CRP…
The objective of this study is to determine the ability of respiratory EMG measurements with a wearable to …
Our objective is to compare the efficacy of early chest tube removal combined with single-shot PVB versus standard treatment (chest tube for at least 3 days and thoracic epidural analgesia (TEA)) after surgery for PSP. Efficacy is defined as…
In the present pilot study, we intend to test phenotypic flexibility (Phenflex) in 20 clinically stable patients with COPD by exploring their response to a dietary challenge test before and after pulmonary rehabilitation. Moreover, the…
To investigate the physiological and structural adaptations of peripheral muscle function at a cellular level in response to EBV treatment.
An Open-label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
To evaluate the long-term safety and tolerability of inhaled treprostinil in subjects with IPF.
Our primary objective is to determine the relationship between immunological profiles and disease course in long-COVID, by characterizing phenotypic and functional changes in (virus-specific) immune cells, , as well as epigenetic and transcriptomic…
The objective of this study is to establish the clinical performance of VENTANA PD-L1 (SP263) CDx Assay as a companion diagnostic (CDx) for the identification of patients with NSCLC who may benefit from treatment with [redacted]. …
This study is to investigate the safety and effectiveness of the AeriSeal system in limiting collateral ventilation within a target lung lobe. And to achieve lung volume reduction using Zephyur Vavles and assess lung function, hyperinflations and…
This research's goal is to develop an artificial intelligence (AI) model that can predict when a child is at risk of experiencing an asthma exacerbation and what their personal risk factors are. The model should be both accurate and…
The aim of this study is twofold. Project 1: to determine in what percentage of patients, who have visited the emergency room for an asthma exacerbation, follow-up is scheduled, at what time and with which healthcare provider, what patient…
Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…