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Prediction of Freezing of Gait and evaluation of the Parkinson's Vibrating Socks during daily-life activities in a house-like environment for people with Parkinson's disease.

To develop a FOG prediction algorithm under free-living conditions, and to test evaluate the use of the Parkinson's Vibrating socks under the same conditions

Forearm immobilization in T2D (FIT2D)

To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.

Sequential imaging for suspicion of Prostate cancer Reducing Overdiagnosis and Unnecessary biopsy with Timely diagnosis of significant cancer

The primary objectives of this study are to evaluate the safety and effectiveness of a novel diagnostic approach applying PSA-density and MRI-imaging-based monitoring, as opposed to immediate prostate biopsy, in men with an intermediate risk of…

Establishing a Controlled Human Infection Model with the Chikungunya live attenuated vaccine VLA1553 in healthy volunteers

The main objective of this study is to establish a controlled human infection model for Chikungunya using the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…

Neurawear: integrating physiological information into forensic care

The proposed study aims to develop a new dashboard (Wearalyze) and design a new user interface in co-creation with therapists, patients and experts in technology to enhance its usability and acceptability. In addition, we explore …

BIO-006

Primary ObjectiveTo assess the safety, feasibility and frequency of relapsing P. vivax PvW1 infection after experimental sporozoite-administered Controlled Human Malaria Infection (CHMI)Secondary ObjectivesTo assess the immune response to primary…