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Establishing a Controlled Human Infection Model with the Chikungunya live attenuated vaccine VLA1553 in healthy volunteers

The main objective of this study is to establish a controlled human infection model for Chikungunya using the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…

Meaningful digital biomarkers for longitudinal monitoring of obstructive sleep apnea around diagnosis and during titration of treatment with CPAP or MAD

Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…