79 results
First ObjectiveIn this study we compare a policy of labour induction at 41 weeks with a policy of expectant management until 42 weeks, with an outpatient check for CTG monitoring and ultrasound measurement in the 42nd week, with respect to the…
In view of this lack of evidence and strong practice variation we propose a randomized clinical trial in overweight and obese subfertile women, in which we compare the costs and effects of a six months structured lifestyle program, aimed at weight…
To investigate the effect of maternal hyperoxygenation with 100% in the second stage of labor and in the presence of abnormal fetal heart rate (FHR) patterns on fetal condition, instrumental delivery rate and free radical production. In case a…
The primary objective is to assess feasibility of a food supplement (multispecies probiotic) placebo-controlled, randomised controlled, double blind intervention in pregnant women in their late second/third trimester of pregnancy, to reduce symptoms…
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
We hypothesize that formerly pre-eclamptic women have persistently increased angiotensin II sensitivity, sodium sensitivity, insulin resistance and sympathetic nerve activity together initially leading to susceptibility for early renal disease and…
1. To evaluate and compare the impact of hysteroscopic Essure® intratubal device placement and laparoscopic salpingectomy on IVF-ET outcomes of patients with hydrosalpinx.2. It is still uncertain whether laparoscopic salpingectomy for hydrosalpinx…
We will examine effectiveness of the internet-based self-help intervention compared to a waiting list control condition on (1) reduction of depressive and anxiety symptoms post intervention and 6 weeks post-partum and (2) improvement in perinatal…
Is there a reduction in uterine closure time and total operation time with the use of monofilament barbed suture, Stratafix?Is there less total blood loss during and after uterine closure?Is there a difference in postoperative recovery and admission…
To assess in term pregnant women with an unfavourable cervix (Bishop score < 6, Appendix1) the effectiveness of induction of labour with a transcervical Foley catheter as compared to induction with misoprostol.
The overall objective of this trial is to generate data on the ovarian stimulation profile obtained when Pergoveris® is started either on stimulation day 1 or stimulation day 6 in ART patients between 36 and 40 years of age (both inclusive). A…
To evaluate whether nitrofurantoin treatment for women with asymptomatic bacteriuria is effective in reducing the risk of preterm delivery and/or pyelonephritis. In addition, assessing whether it is cost-effective to do so.
To assess the effects of a screening policy for Q fever in pregnant women from areas with large numbers of Q fever cases on the pregnancy outcome and cost-effectiveness from a societal and health care perspective.
To assess whether in women with early PPROM tocolytics improve perinatal outcome.
To evaluate the effectivity of the electrohysterogram (EHG) by means of a tocopatch electrode compared to tocodynamometry by means of an external tocodynamometer or intrauterine pressure catheter (IUPC) to monitor trial of labour (TOL) in patients…
Our unique project is based on an ongoing European prenatal stress research focusing on the effect of prenatal stress on early sensory-cognitive development. We capitalize on the methodologically sound maternal and infant physiological measures…
To evaluate whether progesterone treatment for women with a short cervical length is effective in reducing the risk of preterm delivery. In addition to assess whether it is cost-effective to do so.
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
The objective of this study is to gain insights into the value of the proposition *Origo* for women and their loved ones, medical staff and care institution.
The objective of this study is to determine whether retention of cerclage after PPROM improves latency (without a significant increase in chorioamnionitis) and lessens neonatal morbidity.